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Merck

PRKACA

protein kinase, cAMP-dependent, catalytic, alpha

別名:
PKACA
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5566) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18747) protein kinase, cAMP dependent, catalytic, alpha
  • Rat(25636) protein kinase, cAMP-dependent, catalytic, alpha
  • naked mole-rat(101707235) protein kinase, cAMP-dependent, catalytic, alpha
  • sheep(443094) protein kinase, cAMP-dependent, catalytic, alpha
  • domestic guinea pig(100735694) protein kinase, cAMP-dependent, catalytic, alpha
  • dog(403556) protein kinase, cAMP-dependent, catalytic, alpha
  • Horse(100064302) protein kinase, cAMP-dependent, catalytic, alpha
  • cow(282322) protein kinase, cAMP-dependent, catalytic, alpha
  • domestic cat(101090494) protein kinase, cAMP-dependent, catalytic, alpha

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-PKA α antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PKA C-α Antibody, clone 2E17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, mouse, rat
アプリケーション
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-PKA α/β CAT (pThr197) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse
アプリケーション
immunohistochemistry
western blot
Anti-PRKACA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
western blot
ANTI-PKA C-ALPHA/PKA C-BETA(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human, mouse
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
プロテインキナーゼ Aインヒビターフラグメント 14-22, ミリストイル化 トリフルオロアセタート塩, ≥90% (HPLC), lyophilized powder,
Species
mouse, rat, human
チルホスチンA9, solid,
Species
mouse, human
アデニン, ≥99%,
Species
human, rat, mouse
アデニン, BioReagent, suitable for cell culture,
Species
human, rat, mouse
アデニン, BioReagent, suitable for plant cell culture, ≥99%,
Species
human, rat, mouse

Proteins

製品番号
詳細
Species
PKA Protein, Recombinant, 10 µg, Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.,
Species
プロテインキナーゼ A 触媒サブユニット ヒト, >90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Species
human
プロテインキナーゼ A ウシ心臓由来, ≥0.8 units/μg protein, lyophilized powder,
Species
cow

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Prkaca,
Species
mouse
MISSION® esiRNA, targeting human PRKACA,
Species
human