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Merck

MTNR1A

melatonin receptor 1A

別名:
MEL-1A-R, MT1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4543) Summary: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
  • Mouse(17773) melatonin receptor 1A
  • Rat(114211) melatonin receptor 1A
  • dog(482904) melatonin receptor 1A
  • sheep(443022) melatonin receptor 1A
  • chicken(396319) melatonin receptor 1A
  • naked mole-rat(101719975) melatonin receptor 1A
  • domestic guinea pig(100720785) melatonin receptor 1A
  • cow(539948) melatonin receptor 1A
  • domestic cat(101098297) melatonin receptor 1A

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Small Molecule - Agonist

製品番号
詳細
Species
6-ヒドロキシメラトニン, ,
Species
human
Ramelteon, ,
Species
human
アゴメラチン, ≥98% (HPLC),
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
ルジンドール, ≥90%,
Species
human
アゴメラチン, ≥98% (HPLC),
Species
human
メラトニン, powder, ≥98% (TLC),
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-MTNR1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

Small Molecule - Ligand

製品番号
詳細
Species
メラトニン, powder, ≥98% (TLC),
Species
human

Small Molecule - Precursor

製品番号
詳細
Species
N-アセチル-5-ヒドロキシトリプタミン, ≥99% (HPLC), powder,
Species
human

Proteins

製品番号
詳細
Species
ChemiSCREEN Membrane Preparation Recombinant Human MT1 Melatonin Receptor, ,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human MTNR1A,
Species
human