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Merck

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

別名:
5-HT(2B), 5-HT2B
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

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Small Molecule - Agonist

製品番号
詳細
Species
BW 723C86, ≥98% (HPLC),
Species
human
Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,
Species
human
システム適合性用メチルエルゴメトリン, European Pharmacopoeia (EP) Reference Standard,
Species
human
α-メチルセロトニン マレイン酸塩, ≥98% (HPLC),
Species
human
ノルトリプチリン 塩酸塩, ≥98% (HPLC), powder,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,
Species
human
システム適合性用メチルエルゴメトリン, European Pharmacopoeia (EP) Reference Standard,
Species
human
ケタンセリン (+)-酒石酸塩, ≥97%, solid,
Species
human
シクロベンザプリン 塩酸塩, ,
Species
human
シプロヘプタジン 塩酸塩 セスキ水和物, ≥98% (TLC), solid,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
抗HTR2B ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunofluorescence

western blot
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-Htr2B Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14576, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
western blot

Small Molecule - Blocker

製品番号
詳細
Species
ミアンセリン 塩酸塩, ,
Species
human
トリミプラミン マレイン酸塩, ≥98% (TLC), powder,
Species
human
ジメリジン 二塩酸塩, solid,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
ノルトリプチリン 塩酸塩, ≥98% (HPLC), powder,
Species
human
アモキサピン, ,
Species
human
S-(+)-フルオキセチン 塩酸塩, ≥98% (HPLC), solid,
Species
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
フルオキセチン 塩酸塩, solid,
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

製品番号
詳細
Species
5-ヒドロキシインドール-3-酢酸, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
ミフェプリストン, ≥98%,
Species
human, mouse, rat
クロザピン, ,
Species
human, rat

Small Molecule - Precursor

製品番号
詳細
Species
5-ヒドロキシ-L-トリプトファン, powder,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human HTR2B,
Species
human