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Merck

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

別名:
5-HT2A, HTR2
Species:
Human HTR2A (3356), Mouse Htr2a (15558), Rat Htr2a (29595), dog HTR2A (403882), naked mole-rat Htr2a (101708395), Horse HTR2A (100009685), chicken HTR2A (428070), domestic guinea pig Htr2a (100135545), domestic cat HTR2A (101081108), cow HTR2A (407230)
UniProtKB ID:
P28223, B2RAC5, B4DZ79, F5GWE8, Q5T8C0
遺伝子ID:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

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Small Molecule - Agonist

製品番号
詳細
Species
A-119
アリピプラゾール 溶液, 1.0 mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
M110
α-メチルセロトニン マレイン酸塩, ≥98% (HPLC),
Species
human
N7261
ノルトリプチリン 塩酸塩, ≥98% (HPLC), powder,
Species
human
M2525
ミアンセリン 塩酸塩, ,
Species
human
T6154
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
D9190
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
M3324
M100907, ≥98% (HPLC),
Species
human
H-030
Haloperidol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
D206709
2,2-ジフェニルエチルアミン, 96%,
Species
rat
1303002
ハロペリドール, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR1724
ハロペリドール, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
MABN1595
Anti-Serotonin receptor 2A/HTR2A Antibody, clone 9B11.1, clone 9B11.1, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
SAB4301791
抗HTR2A抗体, affinity isolated antibody,
交差性
human, rat
アプリケーション
immunohistochemistry
western blot
SAB4501474
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
SAB2101106
抗HTR2A抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human
アプリケーション
western blot
PC176
Anti-Serotonin 2A (5-HT2A) Receptor (22-41) Rabbit pAb, liquid, Calbiochem®,
交差性
mouse, rat, sheep
アプリケーション

Small Molecule - Blocker

製品番号
詳細
Species
M2525
ミアンセリン 塩酸塩, ,
Species
human
T6154
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human
P1793
ピモジド, ,
Species
human, mouse, rat
T3146
トリミプラミン マレイン酸塩, ≥98% (TLC), powder,
Species
human
Z101
ジメリジン 二塩酸塩, solid,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
128945
フェネチルアミン, 99%,
Species
rat, mouse, human
241008
フェネチルアミン, ≥99%,
Species
rat, mouse, human
T-030
Trazodone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
407267
フェネチルアミン, purified by redistillation, ≥99.5%,
Species
rat, mouse, human
BP591
トラゾドン 塩酸塩, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

製品番号
詳細
Species
H8876
5-ヒドロキシインドール-3-酢酸, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
M8046
ミフェプリストン, ≥98%,
Species
human, mouse, rat
H1512
ハロペリドール, powder,
Species
human, rat
C6305
クロザピン, ,
Species
human, rat

Small Molecule - Precursor

製品番号
詳細
Species
H9772
5-ヒドロキシ-L-トリプトファン, powder,
Species
human

esiRNA

製品番号
詳細
Species
EMU023531
MISSION® esiRNA, targeting mouse Htr2a,
Species
mouse