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Merck

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

別名:
5-HT2A, HTR2
Species:
Human HTR2A (3356), Mouse Htr2a (15558), Rat Htr2a (29595), dog HTR2A (403882), naked mole-rat Htr2a (101708395), Horse HTR2A (100009685), chicken HTR2A (428070), domestic guinea pig Htr2a (100135545), domestic cat HTR2A (101081108), cow HTR2A (407230)
UniProtKB ID:
P28223, B2RAC5, B4DZ79, F5GWE8, Q5T8C0
遺伝子ID:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

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Small Molecule - Agonist

製品番号
詳細
Species
A-119
アリピプラゾール 溶液, 1.0 mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
M110
α-メチルセロトニン マレイン酸塩, ≥98% (HPLC),
Species
human
N7261
ノルトリプチリン 塩酸塩, ≥98% (HPLC), powder,
Species
human
M2525
ミアンセリン 塩酸塩, ,
Species
human
T6154
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
D9190
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
M3324
M100907, ≥98% (HPLC),
Species
human
H-030
Haloperidol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
D206709
2,2-ジフェニルエチルアミン, 96%,
Species
rat
1303002
ハロペリドール, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR1724
ハロペリドール, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
MABN1595
Anti-Serotonin receptor 2A/HTR2A Antibody, clone 9B11.1, clone 9B11.1, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
SAB4301791
抗HTR2A抗体, affinity isolated antibody,
交差性
human, rat
アプリケーション
immunohistochemistry
western blot
SAB2101106
抗HTR2A抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human
アプリケーション
western blot
SAB4501474
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
PC176
Anti-Serotonin 2A (5-HT2A) Receptor (22-41) Rabbit pAb, liquid, Calbiochem®,
交差性
mouse, rat, sheep
アプリケーション

Small Molecule - Blocker

製品番号
詳細
Species
M2525
ミアンセリン 塩酸塩, ,
Species
human
T6154
トラゾドン 塩酸塩, ≥99% (HPLC), powder,
Species
human
P1793
ピモジド, ,
Species
human, mouse, rat
T3146
トリミプラミン マレイン酸塩, ≥98% (TLC), powder,
Species
human
Z101
ジメリジン 二塩酸塩, solid,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
128945
フェネチルアミン, 99%,
Species
rat, mouse, human
241008
フェネチルアミン, ≥99%,
Species
rat, mouse, human
T-030
Trazodone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
407267
フェネチルアミン, purified by redistillation, ≥99.5%,
Species
rat, mouse, human
BP591
トラゾドン 塩酸塩, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

製品番号
詳細
Species
H8876
5-ヒドロキシインドール-3-酢酸, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
M8046
ミフェプリストン, ≥98%,
Species
human, mouse, rat
H1512
ハロペリドール, powder,
Species
human, rat
C6305
クロザピン, ,
Species
human, rat

Small Molecule - Precursor

製品番号
詳細
Species
H9772
5-ヒドロキシ-L-トリプトファン, powder,
Species
human

esiRNA

製品番号
詳細
Species
EMU023531
MISSION® esiRNA, targeting mouse Htr2a,
Species
mouse