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Merck

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

別名:
EIG10, EJM7, GEFSP5
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
  • Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
  • Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
  • chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
  • cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
  • dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
  • sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
  • naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta

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Small Molecule - Agonist

製品番号
詳細
Species
メプロバマート 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
オキサゼパム, ,
Species
human
メプロバマート, United States Pharmacopeia (USP) Reference Standard,
Species
human
メプロバマート, analytical standard,
Species
human
2-ブロモ-2-クロロ-1,1,1-トリフルオロエタン, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
ミダゾラム 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
ジアゼパム 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
オキサゼパム 溶液, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
アルプラゾラム 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
エトミデート, >98% (HPLC), powder,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
フルマゼニル, United States Pharmacopeia (USP) Reference Standard,
Species
human
フルニトラゼパム, ,
Species
human
クロナゼパム, powder,
Species
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
ジアゼパム, ,
Species
human, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, dog, human, mouse, rabbit
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GABRD,
Species
human
MISSION® esiRNA, targeting mouse Gabrd,
Species
mouse