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Merck

GABRB3

gamma-aminobutyric acid (GABA) A receptor, beta 3

別名:
ECA5
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2562) Summary: This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013]
  • Mouse(14402) gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
  • Rat(24922) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • Zebrafish(566922) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • chicken(396290) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • Horse(100050803) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • cow(529593) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • dog(606913) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • sheep(101114905) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • domestic cat(100286790) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • domestic guinea pig(100731340) gamma-aminobutyric acid (GABA) A receptor, beta 3
  • naked mole-rat(101711687) gamma-aminobutyric acid (GABA) A receptor, beta 3

Custom & Knockdown Gene Products

Small Molecule - Agonist

製品番号
詳細
Species
ガボキサドール 塩酸塩, solid, ≥98% (HPLC),
Species
human
ムシモール 臭化水素酸塩, ≥98% (HPLC), solid,
Species
human
イソグバシン 塩酸塩, solid,
Species
human
ピペリジン-4-硫酸, ,
Species
human
メプロバマート 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
デヒドロイソアンドロステロン3-硫酸 ナトリウム塩 二水和物, ≥93% (TLC), powder,
Species
human
5α-Pregnan-3α-ol-11,20-dione, powder, ≥98% (TLC),
Species
human
3α,21-ジヒドロキシ-5α-プレグナン-20-オン, ≥95%,
Species
human
trans-デヒドロアンドロステロン, ≥99%,
Species
human, rat
ペントバルビタール 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
ピクロトキシン, powder,
Species
human
硫酸プレグネノロン ナトリウム塩, ,
Species
human
SR-95531, ≥98% (HPLC), powder,
Species
human
3α,21-ジヒドロキシ-5α-プレグナン-20-オン, ≥95%,
Species
human
trans-デヒドロアンドロステロン, ≥99%,
Species
human, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
抗GABRB3 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
canine, human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
抗GABRB3抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
immunohistochemistry
western blot
Monoclonal Anti-GABRB3 antibody produced in mouse, clone S87-25, 1 mg/mL, purified immunoglobulin,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
NO-711 塩酸塩, ≥98% (HPLC),
Species
human
(±)-ビガバトリン, ,
Species
human
2,6-ジイソプロピルフェノール, 97%,
Species
human
トピラマート, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
トピラマート 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
エトミデート, >98% (HPLC), powder,
Species
human
フルマゼニル, >99% (HPLC), solid,
Species
rat, human
カルバマゼピン, powder,
Species
rat, human
2-ブロモ-2-クロロ-1,1,1-トリフルオロエタン, ≥99%,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GABRB3,
Species
human