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Merck

CTSB

cathepsin B

別名:
APPS, CPSB
Species:
Human CTSB (1508), Mouse Ctsb (13030), Rat Ctsb (64529), domestic guinea pig Ctsb (100714169), naked mole-rat Ctsb (101709008), dog CTSB (486077), Horse CTSB (100060963), domestic cat CTSB (101084873), cow CTSB (281105), sheep CTSB (780470)
UniProtKB ID:
P07858, B3KQR5, B3KRR5, Q503A6, Q96D87
遺伝子ID:
  • Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13030) cathepsin B
  • Rat(64529) cathepsin B
  • domestic guinea pig(100714169) cathepsin B
  • naked mole-rat(101709008) cathepsin B
  • dog(486077) cathepsin B
  • Horse(100060963) cathepsin B
  • domestic cat(101084873) cathepsin B
  • cow(281105) cathepsin B
  • sheep(780470) cathepsin B
  • chicken(396329) cathepsin B

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Antibodies

製品番号
詳細
交差性
アプリケーション
HPA018156
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
IM27L
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
交差性
bovine, human, porcine
アプリケーション
SAB5702092
Anti-Cathepsin B Antibody, clone 6I5D7, Rabbit Monoclonal, ,
交差性
human
アプリケーション
immunohistochemistry
western blot
HPA048998
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
C6243
モノクローナル抗カテプシンB抗体 マウス宿主抗体, clone CB59-4B11, purified from hybridoma cell culture,
交差性
human, rat
アプリケーション
ELISA
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
C2211
Z-Leu-Leu-Leu-al, ≥90% (HPLC),
Species
human
A6185
カルパインインヒビター I, ≥97% (TLC), powder,
Species
human
SML1135
MG-132(R), ≥95% (HPLC),
Species
human
213810
ジエチルシアナミド, 99%,
Species
human

Proteins

製品番号
詳細
Species
C8571
カテプシンB ヒト肝臓由来由来, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Species
human
C6286
カテプシンB from bovine spleen, lyophilized powder, ≥10 units/mg protein,
Species
cow
219362
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Species
human
C0150
カテプシンB ヒト胎盤由来, lyophilized powder, ≥5 units/mg protein,
Species
human
SRP0289
Cathepsin B Active human, recombinant, expressed in FreeStyle™ 293-F cells, ≥90% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
EMU034841
MISSION® esiRNA, targeting mouse Ctsb,
Species
mouse
EHU085641
MISSION® esiRNA, targeting human CTSB,
Species
human

Small Molecule - Substrate

製品番号
詳細
Species
C5429
Z-Arg-Arg-7-アミド-4-メチルクマリン 塩酸塩, ,
Species
mouse, human, rat