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Merck

CDK1

cyclin-dependent kinase 1

別名:
CDC2, CDC28A, P34CDC2
Species:
Human CDK1 (983), Mouse Cdk1 (12534), Rat Cdk1 (54237), dog CDK1 (488997), Zebrafish cdk1 (80973), chicken CDK1 (396252), naked mole-rat Cdk1 (101717463), domestic guinea pig Cdk1 (100735946), Goat CDK1 (100861361), cow CDK1 (281061)
UniProtKB ID:
P06493, A8K7C4, C9J497, O60764
遺伝子ID:
  • Human(983) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(12534) cyclin-dependent kinase 1
  • Rat(54237) cyclin-dependent kinase 1
  • dog(488997) cyclin-dependent kinase 1
  • Zebrafish(80973) cyclin-dependent kinase 1
  • chicken(396252) cyclin-dependent kinase 1
  • naked mole-rat(101717463) cyclin-dependent kinase 1
  • domestic guinea pig(100735946) cyclin-dependent kinase 1
  • Goat(100861361) cyclin-dependent kinase 1
  • cow(281061) cyclin-dependent kinase 1
  • sheep(100216432) cyclin-dependent kinase 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
SAB6012224
Anti-phospho-CDK1/2/3(Thr14) Antibody, clone 23GB1430, Rabbit Monoclonal, clone 23GB1430, recombinant rabbit monoclonal, expressed in HEK293 cells,
交差性
human, rat
アプリケーション
flow cytometry
immunofluorescence
western blot
MABE229
Anti-phospho-Cdk1 (Thr14, Tyr15)Antibody, clone CP3.2, clone CP3.2, from mouse,
交差性
human
アプリケーション
immunocytochemistry
western blot
SAB5700285
Anti-Phospho-CDK1-T14 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
western blot
SAB5700601
Anti-CDK1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
SAB5700350
Anti-Phospho-CDK1-T161 antibody produced in rabbit, ,
交差性
human, mouse
アプリケーション
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
SML1254
R547, ≥98% (HPLC),
Species
human
F3055
フラボピリドール 塩酸塩 水和物, ≥98% (HPLC), powder,
Species
human
R7772
ロスコビチン, ≥98% (TLC),
Species
human, mouse, rat

Proteins

製品番号
詳細
Species
SRP5009
CDK1/サイクリンB1、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
C0244
CDK1/サイクリンA2、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
EHU099351
MISSION® esiRNA, targeting human CDK1,
Species
human