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Merck

BRD2

bromodomain containing 2

別名:
D6S113E, FSH, FSRG1, NAT, RING3, RNF3
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6046) Summary: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(14312) bromodomain containing 2
  • Rat(294276) bromodomain containing 2
  • domestic guinea pig(100734555) bromodomain containing 2
  • cow(505358) bromodomain containing 2
  • Domestic Rabbit(100343906) bromodomain containing 2
  • domestic cat(101084362) bromodomain containing 2
  • sheep(101110276) bromodomain containing 2
  • chicken(417049) bromodomain containing 2
  • dog(474868) bromodomain containing 2
  • naked mole-rat(101699681) bromodomain containing 2

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Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-BRD2 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-BRD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-BRD2 Antibody, from rabbit, purified by affinity chromatography,
交差性
human, rat
アプリケーション
immunohistochemistry
western blot
Goat anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
交差性
human
アプリケーション
western blot
Rabbit anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
交差性
human, mouse
アプリケーション
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
I-BET762, ≥98% (HPLC),
Species
human
OTX015, ≥98% (HPLC),
Species
human

Proteins

製品番号
詳細
Species
BRD2, BD1, BD2 (65-459) GST tag human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
BRD2 (339-459) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human
BRD2 (65-187) GST tag human, recombinant, expressed in E. coli, ≥81% (SDS-PAGE),
Species
human
BRD2 (65-187) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human
BRD2 (339-459) GST tag human, recombinant, expressed in E. coli, ≥86% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Brd2,
Species
mouse
MISSION® esiRNA, targeting human BRD2,
Species
human