575608-U
Discovery® DSC-Si 96-well solid phase extractio (SPE) Plate
bed wt. 50 mg/well, pk of 1
Sinonimo/i:
Silica SPE 96-well plate
About This Item
Prodotti consigliati
product name
Discovery® DSC-Si SPE 96-well Plate, bed wt. 50 mg/well, pk of 1
Materiali
PE frit (20 μm)
polypropylene hardware
Composizione
bed wt., 50 mg/well
Confezionamento
pk of 1
tecniche
solid phase extraction (SPE): suitable
Area superficiale
480 m2/g
Matrice
silica gel base material (irregularly shaped, acid washed)
Gruppo funzionale matrice
silica bonding
Dimensione particelle
50 μm
Dimensione pori
70 Å pore size
applicazioni
food and beverages
Tecnica di separazione
normal phase
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Descrizione generale
Sample Matrix Compatibility: Organic solvents, oils, and lipids
- Unbonded acid washed silica sorbent ideal for normal phase SPE and other modified flash techniques
- Often used to separate or remove structurally similar molecules through successive elutions with increasingly polar solutions
- The most polar normal phase sorbent available
- Excellent capacity for purifying solution phase combinatorial chemistry reactions when removing target molecules from reaction by-products and excess reagents
- Available in Büchner Funnel configurations for easy scalability
Applicazioni
- High-Throughput Mass Spectrometry for Biopharma: Utilizes the Discovery DSC-Si SPE 96-well plate for rapid and accurate biomolecule characterization, demonstrating its critical role in high-throughput analytical setups, enhancing productivity in biopharmaceutical analysis (Campuzano et al., 2022).
- Towards a Point-of-Care Diagnostic Platform for Multiplex Sensing: Highlights the application of Discovery DSC-Si SPE 96-well plates in developing advanced diagnostic platforms, specifically for detecting mild traumatic brain injury biomarkers, showcasing the plate′s versatility and reliability in clinical settings (Jović et al., 2022).
- Determination of Crizotinib in Plasma by LC-ESI-MS/MS: Demonstrates the use of Discovery DSC-Si SPE 96-well plates in pharmacokinetic studies, providing robust and efficient sample preparation methods for therapeutic drug monitoring and clinical research (Roberts et al., 2014).
- High-throughput Mass Spectrometric Cytochrome P450 Inhibition Screening: Applies the Discovery DSC-Si SPE 96-well plate in drug metabolism studies, specifically in the screening of cytochrome P450 enzyme inhibitors, which is crucial for predicting drug-drug interactions in drug development (Lim et al., 2013).
- Development of a High-Throughput SPE/MS Method for Cytochrome P450 Inhibition: Uses the Discovery DSC-Si SPE 96-well plate to enhance throughput in the pharmacological screening of drug candidates, underscoring its importance in the early stages of drug discovery to assess potential toxicities (Lim et al., 2010).
Note legali
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Contenuto correlato
Solid phase extraction purifies samples for chromatographic analysis, improving data quality and protecting analytical columns.
L’estrazione in fase solida (SPE) è una tecnica impiegata per una rapida, selettiva preparazione e purificazione del campione prima di analisi cromatografiche (es. HPLC, GC, TLC). Si usa la SPE per lo scambio di matrici dei campioni, la concentrazione degli analiti e la rimozione di interferenze e contaminanti, al fine di migliorare i risultati e proteggere la colonna analitica.
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
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