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442785

Supelco

Squalene

analytical standard

Sinonimo/i:

2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene

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1000 MG
675,00 €

675,00 €

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1000 MG
675,00 €

About This Item

Formula condensata:
[(CH3)2C[=CHCH2CH2C(CH3)]2=CHCH2-]2
Numero CAS:
111-02-4
Peso molecolare:
410.72
Beilstein:
1728919
Numero CE:
203-826-1
Numero MDL:
MFCD00008912
Codice UNSPSC:
12352200
ID PubChem:
24867671

675,00 €

Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Richiedi un ordine bulk

Grado

analytical standard

Livello qualitativo

100

CdA

current certificate can be downloaded

Confezionamento

ampule of 1000 mg

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Indice di rifrazione

n20/D 1.494 (lit.)

P. ebollizione

285 °C/25 mmHg (lit.)

Punto di fusione

−75 °C (lit.)

Densità

0.858 g/mL at 25 °C (lit.)

applicazioni

environmental
food and beverages

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

CC(C)=CCCC(C)=CCCC(C)=CCC\C=C(/C)CCC=C(C)CCC=C(C)C

InChI

1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+
YYGNTYWPHWGJRM-AAJYLUCBSA-N

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Categorie correlate

Descrizione generale

Squalene is a naturally occurring triterpenoid and a precursor to sterol biosynthesis. Typically isolated from shark liver, olive, amaranth, and algal oils, it shows various cosmetic and medicinal uses.

Applicazioni

This analytical standard can also be used as follows:

  • Analysis of 119 vegetable oil samples from 7 different varieties to detect and determine squalene and four sterols using a developed and validated non-destructive method based on proton nuclear magnetic resonance (1H NMR) spectroscopy combined with partial least squares (PLS) method
  • Determination of squalene in different oil samples by gas chromatography coupled to flame ionization detection (GC-FID) following base-catalyzed transmethylation of the oil base
  • Ultra-high performance liquid chromatography-photodiode array detection (UHPLC-PDA) based quantification of squalene, following its single-step solid phase extraction (SPE) from 33 samples of extra virgin olive oil collected from different countries
  • Measurement of squalene content of 16 commercial shark liver oil samples using a gas chromatography-mass spectrometry-based method, in addition to IR and Raman spectroscopy combined with the PLS method
  • Multi-residue determination of 14 naturally occurring compounds— squalene, tocopherols, and phytosterols, following their solid phase extraction (SPE) from 15 vegetable oil samples by GC-MS

Altre note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H304

Consigli di prudenza

P301 + P310 + P331

Classi di pericolo

Asp. Tox. 1

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
LC26705V
LC24616V
LC15425V
LC07421V
LC01194V

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Christine Durier et al.
AIDS (London, England), 27(1), 87-93 (2012-09-29)
In immunocompromised patients, alternative schedules more immunogenic than the standard influenza vaccine regimen are necessary to enhance and prolong vaccine efficacy. We previously reported that the AS03A-adjuvanted 2009 A/H1N1v vaccine yielded a higher short-term immune response than the nonadjuvanted one
F Rubinstein et al.
BMJ (Clinical research ed.), 346, f393-f393 (2013-02-06)
To assess the risk of adverse perinatal events of vaccination of pregnant women with an MF59 adjuvanted vaccine. Cross sectional multicentre study. 49 public hospitals in major cities in Argentina, from September 2010 to May 2011. 30,448 mothers (7293 vaccinated)
Minh T Ta et al.
The FEBS journal, 279(22), 4231-4244 (2012-09-28)
The isoprenoid squalene is an important precursor for the biosynthesis of sterols. The cellular storage of squalene and its impact on membrane properties have been the subject of recent investigations. In a screen for abnormal lipid droplet morphology and distribution
Mark J Mulligan et al.
JAMA, 312(14), 1409-1419 (2014-10-08)
Human infections with avian influenza A/H7N9 have resulted in high morbidity and mortality in China. To compare safety and immunogenicity of different doses of influenza A/Shanghai/2/13 (H7N9) vaccine mixed with or without the MF59 adjuvant. Multicenter, randomized, double-blind, phase 2
Marco Villa et al.
American journal of epidemiology, 178(7), 1139-1145 (2013-07-19)
MF59-adjuvanted trivalent influenza vaccine (Novartis Vaccines and Diagnostics, Siena, Italy) has been shown to be more effective than nonadjuvanted vaccine in the elderly population. Here we present results from a large-scale, observational, noninterventional, prospective postlicensure study that evaluated the safety
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

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