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V4015

Sigma-Aldrich

Verbascoside

≥99% (HPLC)

Sinonimo/i:

Acetoside, Kusaginin

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10 MG
710,60 €

710,60 €

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10 MG
710,60 €

About This Item

Formula empirica (notazione di Hill):
C29H36O15
Numero CAS:
61276-17-3
Peso molecolare:
624.59
Numero MDL:
MFCD00221751
Codice UNSPSC:
12352200
ID PubChem:
329829047
NACRES:
NA.25

710,60 €

Prezzo di listino836,00 €Risparmia il 15%
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Richiedi un ordine bulk

Livello qualitativo

200

Saggio

≥99% (HPLC)

applicazioni

metabolomics
vitamins, nutraceuticals, and natural products

Temperatura di conservazione

room temp

Stringa SMILE

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1
FBSKJMQYURKNSU-ZLSOWSIRSA-N

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Categorie correlate

Descrizione generale

Verbascoside, also known as acteoside, is a hydrophilic plant compound first isolated from mullein (Verbascum sinuatum L.).[1] The chemical structure of verbascoside comprises hydroxyphenylethyl and cinnamic acid moieties bound to a β-glucopyranose via a glycosidic bond.[1]

Applicazioni

Verbascoside has been used:
  • as a reference standard for high-performance liquid chromatography (HPLC) analysis[2]
  • as a reference standard for detection of phenolic compounds in olive mill wastewater and pomace by high-performance liquid chromatography (HPLC)-diode-array detector (DAD)-qTOF system[3]
  • to test its anti-viral activity against respiratory syncytial virus (RSV) in HEP2 cells and A549 cells[4]

Azioni biochim/fisiol

Phenylethanoid glycoside. Antioxidant and antiproliferative.
Verbascoside has anti-inflammatory and photoprotective properties.[5] It has shown neuroprotective effects on PC12 neuronal cells against neurotoxicity.[6] Verbascoside is proven to be a potent inhibitor of xanthine oxidase (XOD) in in vitro studies.[7]

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
SLCP4923
SLCQ1161
SLCP8197
SLCP7825
SLCD6521

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Sigma-Aldrich

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Supelco

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04480585

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Guo-Qing Sheng et al.
European journal of pharmacology, 451(2), 119-124 (2002-09-17)
The neuroprotective effects of verbascoside, one of phenylpropanoid glucoside isolated from the Chinese herbal medicine Buddleja officinalis Maxim, on 1-methyl-4-phenylpyridinium ion (MPP(+)) induced apoptosis and oxidative stress in PC12 neuronal cells were investigated. Treatment of PC12 cells with MPP(+) for
Kalina Alipieva et al.
Biotechnology advances, 32(6), 1065-1076 (2014-07-23)
Phenylethanoid glycosides are naturally occurring water-soluble compounds with remarkable biological properties that are widely distributed in the plant kingdom. Verbascoside is a phenylethanoid glycoside that was first isolated from mullein but is also found in several other plant species. It
Yin Wan et al.
International journal of biological macromolecules, 93(Pt A), 609-614 (2016-11-05)
In this study, we analyzed the inhibitory effect of verbascoside against xanthine oxidase (XOD) in vitro by using animal model and in vivo by direct inhibition assay. Results showed that verbascoside could reduce uric acid in rat serum and inhibit
Kiramage Chathuranga et al.
Viruses, 11(7) (2019-07-07)
The herbs Plantago asiatica and Clerodendrum trichotomum have been commonly used for centuries in indigenous and folk medicine in tropical and subtropical regions of the world. In this study, we show that extracts from these herbs have antiviral effects against
Hong-Quan Wang et al.
Neurotoxicity research, 21(4), 368-378 (2011-12-08)
Our previous study has shown that acteoside, an antioxidative phenylethanoid glycoside, protect against beta-amyloid (Aβ)-induced cytotoxicity in vitro. However, the precise protective mechanisms remains unclear. Heme oxygenase-1 (HO-1) is a crucial factor in the response to oxidative injury, protecting neurons
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