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T1875

Sigma-Aldrich

Testosterone propionate

solid

Sinonimo/i:

17β-Hydroxy-4-androsten-3-one 17-propionate, 17β-Propionyloxy-4-androsten-3-one, 4-Androsten-17β-ol-3-one 17-propionate

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About This Item

Formula empirica (notazione di Hill):
C22H32O3
Numero CAS:
57-85-2
Peso molecolare:
344.49
Beilstein:
3221760
Numero CE:
200-351-1
Numero MDL:
MFCD00003653
Codice UNSPSC:
51111800
ID PubChem:
24899994
NACRES:
NA.77

Origine biologica

synthetic (organic)

Livello qualitativo

200

Sterilità

non-sterile

Saggio

≥98% (HPLC)

Forma fisica

solid

Controllo stupefacenti

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

Colore

white

Solubilità

acetone: soluble 1 in 4 of acetone
chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow
ethanol: soluble 1 in 6 of ethanol
ethyl oleate: soluble 1 in 20 of ethyl oleate
propylene glycol: soluble 1 in 30 of propylene glycol
soluble 1 in 20 of ethyl oleate
ethanol: 10 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.4 mg/mL
H2O: insoluble
oil: soluble

Condizioni di spedizione

ambient

Temperatura di conservazione

room temp

Stringa SMILE

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(=O)CC

InChI

1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1
PDMMFKSKQVNJMI-BLQWBTBKSA-N

Informazioni sul gene

human ... AR(367) , CYP17A1(1586)
rat ... Ar(24208)

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Applicazioni

Testosterone propionate has been used for studying its effects on pregnant ewes,.

Azioni biochim/fisiol

Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it regulates several biological functions. Testosterone propionate has been synthetically derived from a plant. This product has extended and faster-acting functions when compared to other testosterone esters.

Stato fisico

Photosensitive solid

Nota sulla preparazione

This product is soluble in chloroform (50 mg/ml). It is also soluble in various oils. The oil solutions can be sterilized by maintaining at 150 deg C for 1 hour. It is practically insoluble in water, soluble 1 in 6 of ethanol, 1 in 4 of acetone, 1 in 20 of ethyl oleate, and 1 in 30 of propylene glycol. The product is incompatible with alkalis and oxidizing agents and it should be protected from light.

Avvertenze

Danger

Indicazioni di pericolo

H302,H351,H360FD,H400

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1A

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

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M E Rose et al.
Infection and immunity, 26(2), 630-637 (1979-11-01)
Comparisons were made between infections with Eimeria spp. in normal animals and in animals with functional deficiencies in either T-lymphocytes (athymic nude rats) or B-lymphocytes (bursectomized chickens). Approximately three times more oocysts of E. nieschulzi were passed during a primary
Maria Cernea et al.
Endocrinology, 156(9), 3277-3291 (2015-06-11)
Prenatal testosterone (T)-treated ewes display a constellation of reproductive defects that closely mirror those seen in PCOS women, including altered hormonal feedback control of GnRH. Kisspeptin/neurokinin B/dynorphin (KNDy) neurons of the arcuate nucleus (ARC) play a key role in steroid
Tsuyoshi Shimmura et al.
Scientific reports, 9(1), 3978-3978 (2019-03-10)
Animals that communicate using sound are found throughout the animal kingdom. Interestingly, in contrast to human vocal learning, most animals can produce species-specific patterns of vocalization without learning them from their parents. This phenomenon is called innate vocalization. The underlying
James J Li et al.
Journal of medicinal chemistry, 50(13), 3015-3025 (2007-06-08)
A novel series of imidazolin-2-ones were designed and synthesized as highly potent, orally active and muscle selective androgen receptor modulators (SARMs), with most of the compounds exhibiting low nM in vitro potency in androgen receptor (AR) binding and functional assays.
Carlo Serra et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 68(1), 17-26 (2012-04-14)
Aging is associated with loss of muscle mass and strength, reduced satellite cell number, and lower regenerative potential. Testosterone increases muscle mass, strength, and satellite cell number in humans; however, the effects of testosterone on the regenerative potential of skeletal
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