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Merck
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Documenti

T1016

Sigma-Aldrich

Trichlormethiazide

≥98%

Sinonimo/i:

6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
(+/-)-, NSC 61560

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About This Item

Formula empirica (notazione di Hill):
C8H8Cl3N3O4S2
Numero CAS:
133-67-5
Peso molecolare:
380.66
Numero CE:
205-118-8
Numero MDL:
MFCD00057315
Codice UNSPSC:
12352200
ID PubChem:
24899924
NACRES:
NA.25

Saggio

≥98%

Stringa SMILE

NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl

InChI

1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
LMJSLTNSBFUCMU-UHFFFAOYSA-N

Informazioni sul gene

human ... SLC12A3(6559)

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Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H317,H334

Consigli di prudenza

P261 - P280 - P342 + P311

Classi di pericolo

Resp. Sens. 1 - Skin Sens. 1

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

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Susumu Ogawa et al.
Hypertension (Dallas, Tex. : 1979), 47(4), 699-705 (2006-03-01)
We tested the hypothesis that blockade of angiotensin II type 1 receptors reduces oxidative stress markers in parallel with urinary albumin and type IV collagen excretions. Sixty-six diabetic patients with nephropathy were randomly assigned to either the angiotensin II receptor
Kenichiro Miura et al.
Pediatric nephrology (Berlin, Germany), 24(6), 1235-1238 (2009-01-21)
The administration of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin type 1 receptor blockers (ARBs) to pregnant women has been reported to cause ACEI/ARB fetopathy, including oligohydramios, pulmonary hypoplasia, renal insufficiency, limb contracture, and fetal hypotension in the child. Most of
I Kuwajima et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 24(5), 475-480 (2001-10-26)
A randomized prospective controlled study, the National Interventional Cooperative Study in Elderly Hypertensives (NICS-EH), previously demonstrated that the preventive effect of the long-acting calcium channel blocker nicardipine on the cardiovascular endpoint was similar to that of the diuretic, trichlormethiazide. The
Takeshi Takami
Hypertension research : official journal of the Japanese Society of Hypertension, 32(12), 1086-1090 (2009-09-26)
Morning hypertension has been reported to be an important risk factor for cardiovascular events, and arterial stiffness bears a relationship with cardiovascular risk. The aim of this study was to evaluate whether high-dose angiotensin II receptor blocker (ARB) treatment has
Haruo Mizuno et al.
Endocrine, 24(1), 55-59 (2004-07-14)
Congenital nephrogenic diabetes insipidus (NDI) is characterized by the insensitivity of the distal nephron to arginine vasopressin. Clinical knowledge of this disease is based largely on case reports. For this study, we investigated the clinical findings of eight patients in
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