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SBR00068

Sigma-Aldrich

Streptomycin Ready Made Solution

100 mg/mL in water

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10 ML
40,30 €

40,30 €


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Cambia visualizzazione
10 ML
40,30 €

About This Item

Numero CAS:
Codice UNSPSC:
51281624
NACRES:
NA.76

40,30 €


Per informazioni sulla disponibilità, contatta il Servizio Clienti.

Stato

liquid

Livello qualitativo

Attività specifica

(Antibacterial)

Concentrazione

100 mg/mL in water

Spettro attività antibiotica

Gram-negative bacteria
Gram-positive bacteria
mycobacteria

Modalità d’azione

protein synthesis | interferes

Temperatura di conservazione

−20°C

Stringa SMILE

[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.[S](=O)(=O)(O)O.N([C@@H]4[C@@H](O[C@H]([C@@H]([C@H]4O)O)CO)O[C@H]5[C@@H](O[C@H]([C@]5(O)C=O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H]([C@@H]6O)O)N=C(N)N)O)N=C(N)N)C.N([C@@H]1[C@@H](O[C@H]([C@@H]([C@H]1O)O)CO)O[C@H]2[C@@H](O[C@H]([

InChI

1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-
QTENRWWVYAAPBI-YZTFXSNBSA-N

Descrizione generale

Chemical structure: aminoglycoside

Applicazioni

Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50 μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.

Azioni biochim/fisiol

Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.

Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.

Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.

Stoccaggio e stabilità

  • Streptomycin ready made solution contains 100 mg/mL streptomycin sulfate in water.
  • Streptomycin: sulfate salt ratio is 1:1.5.
  • The product is packed under aseptic conditions.

Pittogrammi

Health hazard

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Repr. 2

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3


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Domande

  1. Streptomycin ready made solution 100mg/ml cat # SBR00068 : is the solution filtered at the end of the preparation? Thank you

    1 risposta
    1. The details of the manufacturing processing cannot be shared, for proprietary reasons, but the product is not sterile filtered. It is is packaged under aseptic conditions.

      Utile?

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