Anti-SMO antibody detects endogenous levels of total SMO protein.
The SMO (smoothened) gene is mapped to human chromosome 7q32.1. It encodes a protein that belongs to the frizzled family of G protein-coupled receptors. It is a seven transmembrane protein and highly conserved.
Immunogeno
The antiserum was produced against synthesized peptide derived from human SMO.
Immunogen Range: 68-117
Azioni biochim/fisiol
The SMO (smoothened) gene encodes a protein that mediates hedgehog signaling for embryonic development and to maintain tissue homeostasis. SMO participates in tumor cell proliferation.
Caratteristiche e vantaggi
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Stato fisico
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Epigenetics Offer New Horizons for Colorectal Cancer Prevention.
Schnekenburger M and Diederich M
Current Colorectal Cancer Reports, 8(1), 66-81 (2012)
Identification of Novel Smoothened Ligands Using Structure-Based Docking.
Lacroix C
PLoS ONE, 11(8), 1-20 (2016)
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