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Merck
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Key Documents

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P7380

Sigma-Aldrich

Purpurogallin

Sigma Grade

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About This Item

Formula empirica (notazione di Hill):
C11H8O5
Numero CAS:
569-77-7
Peso molecolare:
220.18
Numero CE:
209-324-9
Numero MDL:
MFCD00004145
Codice UNSPSC:
12171500

Grado

Sigma Grade

Punto di fusione

275 °C (dec.) (lit.)

Temperatura di conservazione

−20°C

Stringa SMILE

OC1=CC=Cc2cc(O)c(O)c(O)c2C1=O

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Applicazioni

Calibration standard for peroxidase assays using pyrogallol as substrate.

Azioni biochim/fisiol

Polyphenol antibiotic originally isolated from Quercus nutgall that has antioxidant activity. Competitive inhibitor of epidermal growth factor receptor protein tyrosine kinase activity; inhibitor of xanthine oxidase.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Consigli di prudenza

P261 - P305 + P351 + P338

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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Mairtin O'Coinceanainn et al.
Journal of inorganic biochemistry, 96(4), 463-468 (2003-09-19)
Polyphenols are antioxidants, which are known to influence bioavailability of metals in the body. The theaflavins of black tea are important members of this family, which have been sparsely investigated. The complexation of aluminium with purpurogallin (2,3,4,6-tetrahydroxy-5H-benzocyclohepten-5-one) has been investigated
O Nozaki et al.
Journal of bioluminescence and chemiluminescence, 10(3), 151-156 (1995-05-01)
The effects of various boronate compounds, 4-biphenylboronic acid, 4-bromobenzene-boronic acid, trans-4-(3-propionic acid)phenylboronic acid and 4-iodophenylboronic acid, on the horseradish peroxidase (HRP) catalysed chemiluminescent oxidation of pyrogallol and purpurogallin by peroxide were investigated. trans-4-(3-Propionic acid)phenylboronic acid produced a 13.7-fold enhancement in
Akram Jamshidzadeh et al.
Journal of applied toxicology : JAT, 27(4), 322-326 (2007-02-01)
Chloroquine is a synthetic quinoline being used as an antimalaria and antirheumatoid agent. Several cases of hepatotoxicity have been reported with the use of chloroquine. However, the mechanism(s) of its hepatotoxic effect is unknown. The purpose of this study was
L H Zeng et al.
Cornea, 14(5), 509-514 (1995-09-01)
We reported previously that purpurogallin (PPG) markedly protects the cultured rabbit corneal endothelial cells (RCEC) against oxyradical damage generated with hypoxanthine (HX) and xanthine oxidase (XO)(1). In this study, we further compared the cytoprotective activities of PPG versus Trolox (TX
Shinichi Kitada et al.
Journal of medicinal chemistry, 46(20), 4259-4264 (2003-09-19)
Among the most promising chemopreventive agents, certain natural polyphenols have recently received a great deal of attention because of their demonstrated inhibitory activity against tumorigenesis. In view of their anticancer properties, these compounds also hold great promise as potential chemotherapeutic
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