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Merck
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Documenti

M2381

Sigma-Aldrich

5-Methoxy-N,N-dimethyltryptamine

Sinonimo/i:

3-(2-Dimethylaminoethyl)-5-methoxyindole, 3-[2-(Dimethylamino)ethyl]-5-methoxyindole, 5-MeO-DMT, 5-Methoxy-DMT, 5-OMe-DMT

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Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C13H18N2O
Numero CAS:
1019-45-0
Peso molecolare:
218.29
Numero CE:
213-813-2
Numero MDL:
MFCD00005658
Codice UNSPSC:
41116107
ID PubChem:
24278119

Controllo stupefacenti

USDEA Schedule I; Home Office Schedule 1; kontrollierte Droge in Deutschland

Punto di fusione

69-70 °C (lit.)

Temperatura di conservazione

2-8°C

Stringa SMILE

COc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3
ZSTKHSQDNIGFLM-UHFFFAOYSA-N

Informazioni sul gene

human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR5B(645694) , HTR6(3362) , HTR7(3363)
rat ... Htr1a(24473) , Htr2a(29595) , Htr2b(29581) , Htr2c(25187) , Htr7(65032)

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Azioni biochim/fisiol

Hallucinogen; non-selective serotonin receptor agonist.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H336

Classi di pericolo

STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Thomas S Ray
PloS one, 5(2), e9019-e9019 (2010-02-04)
We currently understand the mental effects of psychedelics to be caused by agonism or partial agonism of 5-HT(2A) (and possibly 5-HT(2C)) receptors, and we understand that psychedelic drugs, especially phenylalkylamines, are fairly selective for these two receptors. This manuscript is
Rafael Vitor Lima da Cruz et al.
Frontiers in molecular neuroscience, 11, 312-312 (2018-09-21)
The subgranular zone (SGZ) of dentate gyrus (DG) is one of the few regions in which neurogenesis is maintained throughout adulthood. It is believed that newborn neurons in this region encode temporal information about partially overlapping contextual memories. The 5-Methoxy-N,N-dimethyltryptamine
Adam L Halberstadt
Pharmacology, biochemistry, and behavior, 143, 1-10 (2016-01-19)
Monoamine oxidase inhibitors (MAOIs) are often ingested together with tryptamine hallucinogens, but relatively little is known about the consequences of their combined use. We have shown previously that monoamine oxidase-A (MAO-A) inhibitors alter the locomotor profile of the hallucinogen 5-methoxy-N,N-dimethyltryptamine
Jessica Winne et al.
Experimental neurology, 326, 113175-113175 (2020-01-11)
Salicylate intoxication is a cause of tinnitus and comorbidly associated with anxiety in humans. In a previous work, we showed that salicylate induces anxiety-like behavior and hippocampal type 2 theta oscillations (theta2) in mice. Here we investigate if the anxiogenic
Vanja Dakic et al.
Scientific reports, 7(1), 12863-12863 (2017-10-11)
Dimethyltryptamines are entheogenic serotonin-like molecules present in traditional Amerindian medicine recently associated with cognitive gains, antidepressant effects, and changes in brain areas related to attention. Legal restrictions and the lack of adequate experimental models have limited the understanding of how
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