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L7414

Sigma-Aldrich

N-Lauroylsarcosine sodium salt solution

20%, for molecular biology

Sinonimo/i:

Sarcosyl, Sarkosyl NL, Sodium N-dodecanoyl-N-methylglycinate, Sodium N-lauroylsarcosinate solution

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About This Item

Formula condensata:
CH3(CH2)10CON(CH3)CH2COONa
Numero CAS:
Peso molecolare:
293.38
Beilstein:
5322974
Numero MDL:
Codice UNSPSC:
12161900
ID PubChem:
NACRES:
NA.25

Grado

for molecular biology

Livello qualitativo

Descrizione

anionic

PM

293.38 g/mol

Concentrazione

19-21% (Titration by HClO4)
20%

Attività estranea

DNase, RNase, and protease, none detected

Stringa SMILE

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
KSAVQLQVUXSOCR-UHFFFAOYSA-M

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Descrizione generale

N-Lauroylsarcosine sodium salt solution is an anionic surfactant which can be used in DNA extraction.

Applicazioni

N-Lauroylsarcosine sodium salt has been used in a study to assess the mechanisms underlying surfactant-induced itching. It has also been used in a study to investigate the formation of pH-responsive, stable vesicles resulting from an interaction with N-cetylpyridinium chloride (CPC) and N-dodecylpyridinium chloride (DPC) in aqueous mixtures.

Caratteristiche e vantaggi

N-Lauroylsarcosine does not precipitate and is commonly used in place of SDS.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

512.6 °F

Punto d’infiammabilità (°C)

267 °C


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Interaction of sodium N-lauroylsarcosinate with N-alkylpyridinium chloride surfactants: Spontaneous formation of pH-responsive, stable vesicles in aqueous mixtures
Ghosh, S. and J. Dey
Journal of Colloid and Interface Science, 358, 9-9 (2011)
Alejandro Álvarez-Quilón et al.
Nature communications, 11(1), 910-910 (2020-02-16)
The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established tumour suppressor whose loss is the cause of the neurodegenerative and cancer-prone syndrome Ataxia-Telangiectasia (A-T). A-T patients and Atm-/- mouse models
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Droplet microfluidics-based platform (Drop-seq) has been shown to be a powerful tool for single cell expression profiling. Nevertheless, this platform required the simultaneous encapsulation of single cell and single barcoded bead, the incidence of which was very low, limiting its
Yoshihiro Inami et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(11), 1225-1230 (2012-11-06)
The primary function of surfactants is to remove dirt, exfoliated corneum cells, and microorganisms from the skin. However, the use of toiletries such as soaps and shampoos containing surfactants may cause adverse effects such as cutaneous irritation, dryness, and itching.

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