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L6135

Sigma-Aldrich

Lectina da Arachis hypogaea (arachide)

biotin conjugate, lyophilized powder

Sinonimo/i:

Agglutinina dell’arachide, PNA

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1 MG
124,00 €
5 MG
326,00 €

124,00 €


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1 MG
124,00 €
5 MG
326,00 €

About This Item

Codice UNSPSC:
12352202
NACRES:
NA.32

124,00 €


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Coniugato

biotin conjugate

Livello qualitativo

Stato

lyophilized powder

PM

120 kDa

Composizione

Protein, ≥80% Lowry

Grado di funzionalizzazione

~3 mol biotin per mol protein

tecniche

blood typing: suitable
fractionation: suitable

Solubilità

water: 1.00-1.10 mg/mL, clear to slightly hazy, colorless

Temperatura di conservazione

2-8°C

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Descrizione generale

Peanut lectin (PNA) is a lectin or an agglutinin from the legume, Arachis hypogaea,[1] found in peripheral venous blood in humans after ingestion of peanuts. PNA lectin is specific to the galactosyl (β-1,3) N-acetylgalactosamine.[1]

Applicazioni

Lectin from Arachis hypogaea (peanut) has been used:
  • in enzyme-linked micro plate assay to detect β-D-galactose-N-acetylglucosamine[2]
  • in Immunohistochemical double staining[3]
  • Immunohistochemical double staining for the detection of germinal centers[4]
  • in enzyme-linked microplate assayto detect β-D-galactose-N-acetylglucosamine[2]

Azioni biochim/fisiol

La PNA non fa agglutinare gli eritrociti umani normali, ma fa agglutinare fortemente gli eritrociti trattati con la neuraminidasi. La PNA esercita una potente attività anti-T analogamente all′anticorpo anti-T nei sieri umani. La lectina può essere utilizzata per distinguere i sottoinsiemi di linfociti umani.
Lectin from Arachis hypogaea (peanut) functions as an antigenic determinant for Thomsen-Friedenreich antigen (TF)[5] and as mitogen for colorectal cancer stimulation cell division in normal colonic epithelium.[6] It is therefore used as tumor marker.[7]

Confezionamento

Package size based on protein content.

Stato fisico

Contains sodium citrate

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Domande

1–3 di 3 domande  
  1. Is the peanut lectin (Lectin from Arachis hypogaea) a glycoprotein?  If so, what is the carbohydrate content?

    1 risposta
    1. Peanut lectin is not a glycoprotein. Although peanut lectin binds specifically to a particular carbohydrate (beta-gal(1-->3)galNac) in other molecules, the lectin itself does not contain any carbohydrate.  Please see page 231 of the following paper: R. Banerjee, et al., "Crystal structure of peanut lectin, a protein with an unusual quaternary structure".  Proc. Nat. Acad. Sci., USA, 91, 227-231 (1994).

      Utile?

  2. What is the Department of Transportation shipping information for this product?

    1 risposta
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Utile?

  3. How does the storage temperature relate to shipping conditions?

    1 risposta
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Utile?

Recensioni

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