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I6005

Sigma-Aldrich

myo-Inositol hexasulfate hexapotassium salt

Sinonimo/i:

Inositol hexakissulfate, InsS6

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About This Item

Formula condensata:
C6H6O24S6K6
Numero CAS:
28434-25-5
Peso molecolare:
889.08
Numero MDL:
MFCD00055894
Codice UNSPSC:
12352201
ID PubChem:
24896081

Temperatura di conservazione

−20°C

Stringa SMILE

[K].OS(=O)(=O)OC1C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C1OS(O)(=O)=O

InChI

1S/C6H12O24S6.K.H/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;/h1-6H,(H,7,8,9)(H,10,11,12)(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24);;
JYVHCOUFXHFSLT-UHFFFAOYSA-N

Azioni biochim/fisiol

InsS6 has a molecular footprint and negative surface charge that is similar to that of phytic acid (InsP6), but with lower biological activity. It is used as a control in studies of the cellular actions of phytic acid. It is also a competitive inhibitor of Aspergillus phytase.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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J M Dabora et al.
The Journal of biological chemistry, 266(35), 23637-23640 (1991-12-15)
Acidic fibroblast growth factor (aFGF) is unstable at physiological temperatures in the absence of polyanions such as heparin. Therefore, the effect of temperature on the kinetics of refolding of aFGF has been examined in the presence and absence of several
Abul H J Ullah et al.
Biochemical and biophysical research communications, 290(4), 1343-1348 (2002-01-29)
The phyA gene from Aspergillus ficuum that codes for a 441-amino-acid full-length phosphomonoesterase (phytase) was cloned and expressed in Medicago sativa (alfalfa) leaves. The expressed enzyme from alfalfa leaves was purified to homogeneity and biochemically characterized, and its catalytic properties
Aaron J Oakley
Biochemical and biophysical research communications, 397(4), 745-749 (2010-06-15)
Phytases hydrolyse the phosphomonoesters of phytate (myo-inositol-1,2,3,4,5,6-hexakis phosphate) and thus find uses in plant and animal production through the mobilisation of phosphorus from this source. The structure of partially deglycosylated Aspergillus niger PhyA is presented in apo form and in
T Otake et al.
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 63(7), 676-683 (1989-07-01)
The monosaccharide substances inositol hexasulfate (IHS) and inositol hexaphosphoric acid (Phytic acid, IHP) were investigated for their antiviral effect on the human immunodeficiency virus (HIV) in vitro. In MT-4 cells IHS completely inhibited the cytopathic effect of HIV and the
J W Wyse et al.
Biochemical and biophysical research communications, 144(2), 779-786 (1987-04-29)
Previous biophysical investigations, including those from our laboratories, have reported that polyphosphates weaken RBC membrane skeletal protein-protein interactions and decrease hemoglobin affinity for oxygen. We have additionally demonstrated that low-affinity intact RBC's may be produced by inositol hexaphosphate (IHP) incorporation
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