E114

EHNA hydrochloride

≥98% (HPLC), powder, adenosine deaminase inhibitor

• Sinonimo/i: erythro-9-(2-Hydroxy-3-nonyl)­adenine hydrochloride, erythro-9-Amino-β-hexyl-­α-methyl-9H-purine-9-ethanol hydrochloride
• Formula empirica (notazione di Hill): C₁₄H₂₃N₅O · HCl
• Numero CAS: 58337-38-5
• Peso molecolare: 313.83
• Numero MDL: MFCD00151066
• Codice UNSPSC: 12352200
• ID PubChem: 24277713
• NACRES: NA.77

Proprietà

• Nome del prodotto: EHNA hydrochloride, ≥98% (HPLC)
• Livello qualitativo: 100
• Saggio: ≥98% (HPLC)
• Condizioni di stoccaggio: desiccated
• Solubilità: DMSO: >10 mg/mL; H₂O: >10 mg/mL
• Stringa SMILE: Cl[H].CCCCCC[C@H]([C@H](C)O)n1cnc2c(N)ncnc12
• InChI: 1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m0./s1; VVDXNJRUNJMYOZ-VZXYPILPSA-N
• Informazioni sul gene: human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140)

Descrizione

Descrizione generale

EHNA is an adenosine deaminase inhibitor. It possesses antitumor action.[1]

Applicazioni

EHNA hydrochloride has been used to treat microexplant culture to examine the direction and the motor responsible for the movement of autophagosomes in axons.[2] It has also been used in nucleoside supplementation to inhibit the breakdown of deoxyadenosine by the enzyme adenosine deaminase.[3]

Azioni biochim/fisiol

Adenosine deaminase inhibitor.

Caratteristiche e vantaggi

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)