A9186

Alcian Blue 8GX

BioReagent, suitable for detection of glycoproteins

• Sinonimo/i: Alcian Blue, Ingrain Blue 1
• Formula empirica (notazione di Hill): C₅₆H₆₈Cl₄CuN₁₆S₄
• Numero CAS: 33864-99-2
• Peso molecolare: 1298.86
• UNSPSC Code: 12171500
• NACRES: NA.32
• PubChem Substance ID: 24891421
• EC Number: 251-705-7
• Colour Index Number: 74240
• MDL number: MFCD00010720

Proprietà

• product line: BioReagent
• Quality Segment: 100
• form: powder
• composition: Dye content, ~50%
• technique(s): electrophoresis: suitable
• suitability: suitable for detection of glycoproteins
• SMILES string: [Cl-].[Cl-].[Cl-].[Cl-].CN(C)C(\SCc1ccc2c3nc(nc4n5[Cu]n6c(nc7nc(nc5c8cc(CS\C(N(C)C)=[N+](\C)C)ccc48)c9ccc(CS\C(N(C)C)=[N+](\C)C)cc79)c%10ccc(CS\C(N(C)C)=[N+](\C)C)cc%10c6n3)c2c1)=[N+](/C)C
• InChI: 1S/C56H68N16S4.4ClH.Cu/c1-65(2)53(66(3)4)73-29-33-17-21-37-41(25-33)49-57-45(37)62-50-43-27-35(31-75-55(69(9)10)70(11)12)19-23-39(43)47(59-50)64-52-44-28-36(32-76-56(71(13)14)72(15)16)20-24-40(44)48(60-52)63-51-42-26-34(18-22-38(42)46(58-51)61-49)30-74-54(67(5)6)68(7)8;;;;;/h17-28H,29-32H2,1-16H3;4*1H;/q+2;;;;;+2/p-4
• InChI key: CKLBXIYTBHXJEH-UHFFFAOYSA-J

Descrizione

General description

Alcian Blue 8GX is a cationic[1] phthalocyanine dye.[2] It has an ability to interact with sulphated glycosaminoglycan.[1] It is used as a counterstain to visualize histological tissue sections. In addition, alcian blue 8GX also aids in the in-situ quantification of marine biofilms produced by marine bacteria.[2]

Application

Alcian Blue 8GX has been used:

• for the quantification of sulphated glycosaminoglycan[1]
• to stain differentiated chondrocytes to access proteoglycan′s synthesis by these cells[3][4]
• to stain Multi-lineage differentiation of hemangioma-derived perivascular cells (Hem-PCs)[4]
• in histological staining to detect neutral and charged carbohydrate residues[5]

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)