49781

Glicerolo

83.5-89.5% (T)

• Sinonimo/i: 1,2,3-Propantriolo
• Formula condensata: HOCH₂CH(OH)CH₂OH · aq
• Numero CAS: 56-81-5
• Peso molecolare: 92.09 (anhydrous basis)
• Beilstein: 635685
• Numero CE: 200-289-5
• Numero MDL: MFCD00004722
• Codice UNSPSC: 50161901
• ID PubChem: 57651222
• NACRES: NA.28
• Saggio: 83.5-89.5% (T)
• tecniche: MALDI-MS: suitable
• P. ebollizione: 182 °C/20 mmHg (lit.)

Proprietà

• Livello qualitativo: 200
• Saggio: 83.5-89.5% (T)
• Stato: viscous liquid
• tecniche: MALDI-MS: suitable
• Impurezze: 10.5-16.5% water
• Residuo alla calcinazione: ≤0.01% (as SO₄)
• P. ebollizione: 182 °C/20 mmHg (lit.)
• Densità: 1.252 g/mL at 25 °C (lit.)
• Stringa SMILE: OCC(O)CO
• InChI: 1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2; PEDCQBHIVMGVHV-UHFFFAOYSA-N

Descrizione

Descrizione generale

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.

Applicazioni

Glycerol solution has been used:

• in the preparation of blood mimicking fluid[1]
• in epidermis mimicking films[2]
• as a constituent of nuclei storage buffer[3]

Azioni biochim/fisiol

Glycerol has been used as

• a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
• a fuel during designing enzymatic biofuel cell.
• a liquid composite matrix with 4-HCCA and 3-amino­quinoline for analysis of neutral and acidic glycans.
• a matrix for fast atom bombardment MS.
• may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.

Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.

Altre note

Substrate for the assay of glycerokinase[4]; glycerol dehydratase[5]; glycerol oxidase[6]

Informazioni sulla sicurezza

• Classe di pericolosità dell'acqua (WGK): WGK 1
• Dispositivi di protezione individuale: Eyeshields, Gloves