460R-1

Heat Shock Protein 70 (EP377) Rabbit Monoclonal Primary Antibody

• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: EP377, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (460R-14); vial of 0.1 mL concentrate Research Use Only (460R-14-RUO); vial of 0.5 mL concentrate (460R-15); vial of 1.0 mL concentrate (460R-16); vial of 1.0 mL concentrate Research Use Only (460R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (460R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (460R-17); vial of 7.0 mL pre-dilute ready-to-use (460R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (460R-18-RUO)
• Produttore/marchio commerciale: Cell Marque^®
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotipo: IgG
• Controllo: hepatocellular carcinoma
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: cytoplasmic, nuclear
• Informazioni sul gene: human ... HSPA1A(3303)

Descrizione

Descrizione generale

The Heat Shock Protein 70 family of highly conserved chaperone proteins increase in expression upon exposure to stress factors such as temperature shock, hypoxia, oxidative stress, and pH change.[1] This promotes cell survival by repairing misfolded proteins and preventing protein aggregates, among other functions.[1] Likewise, tumor cells can use this mechanism to confer a survival advantage as demonstrated in Heat Shock Protein 70 overexpression in hepatocellular carcinoma.[2][3][4][5][1]

Qualità

United States - IVD
European Union - IVD
Japan - RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: [email protected]

Note legali

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2