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Documenti fondamentali

340M-1

Sigma-Aldrich

Thyroglobulin (2H11+6E1) Mouse Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41
Prezzi e disponibilità al momento non sono disponibili

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

diluted ascites fluid

Tipo di anticorpo

primary antibodies

Clone

2H11+6E1, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Stato

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (340M-14)
vial of 0.5 mL concentrate (340M-15)
bottle of 1.0 mL predilute (340M-17)
vial of 1.0 mL concentrate (340M-16)
bottle of 7.0 mL predilute (340M-18)

Produttore/marchio commerciale

Cell Marque®

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG1

Controllo

thyroid

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic

Categorie correlate

Descrizione generale

Thyroglobulin (Tg) is the precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Tg is a high molecular weight glycoprotein found in normal thyroid follicular cells.[1] Thyroglobulin is useful for identifying thyroid origin of carcinoma of papillary and follicular types in the setting of carcinoma of unknown primary.[1][2]

Linkage

Thyroglobulin Positive Control Slides, Product No. 340S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: [email protected]

Note legali

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

Lot/Batch Number
0000425409
0000425409
0000414963
0000414963
0000405697

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A R Judkins et al.
Human pathology, 30(11), 1373-1376 (1999-11-26)
We have previously shown that necrotic tumors retain their immunoreactivity for a range of cytokeratin antibodies. Some thyroid tumors undergo extensive necrosis after fine-needle aspiration (FNA) procedures. We evaluated the sensitivity of antibodies on necrotic thyroid tumors by examining a
Clara S Heffess et al.
Cancer, 95(9), 1869-1878 (2002-10-31)
Clear cell tumors of the thyroid gland in general are uncommon. Metastatic renal cell carcinoma (RCC) to the thyroid gland is a rare occurrence but must be considered in the differential diagnosis of a thyroid gland clear cell neoplasm to
S P Hammar
Human pathology, 29(12), 1393-1402 (1998-12-29)
Adenocarcinomas account for up to 60% of all metastatic neoplasms of unknown primary origin. In general, adenocarcinomas are the most difficult metastatic tumor to accurately identify the primary site. Some metastatic adenocarcinomas have distinctive histological features that allow for their
P A Bejarano et al.
Applied immunohistochemistry & molecular morphology : AIMM, 8(3), 189-194 (2000-09-12)
Thyroid transcription factor-1 (TTF-1), a member of the NKx2 family of homeodomain transcription factors, is a mediator of thyroid-specific transcription of the thyroglobulin (TG) gene. The combined immunohistochemical profile of TTF-1, TG, cytokeratin 7 (CK7), and cytokeratin 20 (CK20) in
D Bellet et al.
The Journal of clinical endocrinology and metabolism, 56(3), 530-533 (1983-03-01)
Human thyroglobulin (Tg) was used as an antigen in the development of antibodies by the hybridoma technique. From four antibodies that bound more than 40% labeled Tg, two were characterized (182/E4 and 211/A5). They were both of the immunoglobulin G

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Recensioni

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