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Merck
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30058

Sigma-Aldrich

Lipase Substrate

≥95% (HPLC)

Sinonimo/i:

1,2-Di-O-lauryl-rac-glycero-3-(glutaric acid 6-methylresorufin ester)

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About This Item

Formula empirica (notazione di Hill):
C45H69NO8
Numero CAS:
Peso molecolare:
752.03
Numero MDL:
Codice UNSPSC:
12352204
ID PubChem:
NACRES:
NA.83

Livello qualitativo

Saggio

≥95% (HPLC)

Forma fisica

powder

Solubilità

ethanol: soluble (10mg/mL)

Fluorescenza

λex 529 nm; λem 600 nm in 0.1 M Tris pH 8.4

Temperatura di conservazione

2-8°C

Stringa SMILE

CCCCCCCCCCCCOCC(COC(=O)CCCC(=O)Oc1ccc2N=C3C=CC(=O)C(C)=C3Oc2c1)OCCCCCCCCCCCC

InChI

1S/C45H69NO8/c1-4-6-8-10-12-14-16-18-20-22-31-50-34-38(51-32-23-21-19-17-15-13-11-9-7-5-2)35-52-43(48)25-24-26-44(49)53-37-27-28-39-42(33-37)54-45-36(3)41(47)30-29-40(45)46-39/h27-30,33,38H,4-26,31-32,34-35H2,1-3H3
FYOMYGYHAZESGQ-UHFFFAOYSA-N

Descrizione generale

Lipase substrate (1,2-Di-O-lauryl-rac-glycero-3-(glutaric,acid 6-methylresorufin) ester, DGGR) is a chromogenic substrate for lipases. It is used in colorimetric methods to measure lipase activity. This substrate produces a red-purple compound, methylresorufin, upon digestion by the lipase enzyme.

Applicazioni

Lipase Substrate is used as substrate in a high‑throughput screening assay to measure the lipase activity in response to lipstatin production

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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Biochemical and biophysical research communications, 488(2), 259-265 (2017-04-24)
Lipases play an important role in physiological metabolism and diseases, and also have multiple industrial applications. Rational modification of lipase specificity may increase the commercial utility of this group of enzymes, but is hindered by insufficient mechanistic understanding. Here, we

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