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Documenti fondamentali

22040

Sigma-Aldrich

β-Carotene

≥97.0% (UV)

Sinonimo/i:

β,β-Carotene, Provitamin A

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About This Item

Formula empirica (notazione di Hill):
C40H56
Numero CAS:
Peso molecolare:
536.87
Beilstein:
1917416
Numero CE:
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
SB.54

Origine biologica

synthetic

Saggio

≥97.0% (UV)

Stato

powder

tecniche

HPLC: suitable

Impurezze

≤0.001% heavy metals

Perdita

≤0.2% loss on drying

Colore

red to dark red

Punto di fusione

176-184 °C (dec.)

Solubilità

chloroform: 10 mg/mL, clear, dark orange-red

Condizioni di spedizione

dry ice

Temperatura di conservazione

2-8°C

Stringa SMILE

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
OENHQHLEOONYIE-JLTXGRSLSA-N

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Applicazioni

  • β-Carotene has been used as a standard to measure β-carotene levels in plasma samples via HPLC (high performance liquid chromatography).[1]
  • It has been used to study the effects of vitamins on growth of Mycobacteria in radiometric culture.[2]
  • It has been used as a supplement in the growth medium of Drosophila melanogaster to allow intake of vitamin A.[3]

Azioni biochim/fisiol

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.
The most important of the provitamins A.

Avvertenza

Purchase minimum quantity required. Discard one month after opening.

Altre note

As a probe of lipid domains of reconstituted human plasma low-density lipoprotein[4]

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

217.9 °F - closed cup

Punto d’infiammabilità (°C)

103.3 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves


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Sigma-Aldrich

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Supelco

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G C Chen et al.
Biochemistry, 19(20), 4706-4712 (1980-09-30)
Mixtures of neutral lipids containing cholesteryl esters and beta-carotene were used to reconstitute the lipid core of heptane-extracted low-density lipoproteins (LDL). The resulting preparations of reconstituted LDL, referred to as r-[cholesteryl ester + beta-carotene]LDL, exhibited temperature-dependent circular dichroism (CD) in
Lack of Dietary Polyunsaturated Fatty Acids Causes Synapse Dysfunction in the Drosophila Visual System.
Ziegler AB, et al.
PLoS ONE, 10, e0135353-e0135353 (2015)
Vitamins A & D inhibit the growth of mycobacteria in radiometric culture.
Greenstein RJ, et al.
PLoS ONE, 7, e29631-e29631 (2012)
Kyeongjin Kim et al.
Experimental & molecular medicine, 41(6), 429-439 (2009-03-27)
Small heterodimer partner (SHP) is an atypical member of nuclear receptor superfamily that lacks a DNA-binding domain. In previous study, we showed that SHP, c-jun, p65 of NF-gammaB subunits, and p21WAF1 expression was increased during monocytic differentiaton with the exposure
Antonio Molino et al.
Molecules (Basel, Switzerland), 24(4) (2019-02-24)
Microalgae Dunaliella salina contains useful molecules such as β-carotene and fatty acids (FAs), which are considered high value-added compounds. To extract these molecules, supercritical carbon dioxide was used at different operative conditions. The effects of mechanical pre-treatment (grinding speed at

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