PHR1216
Dibutyl sebacate
Pharmaceutical Secondary Standard; Certified Reference Material
Sinonimo/i:
Decanedioic acid dibutyl ester, Sebacic acid dibutyl ester
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About This Item
Formula condensata:
[-(CH2)4CO2(CH2)3CH3]2
Numero CAS:
Peso molecolare:
314.46
Beilstein:
1798308
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
certified reference material
pharmaceutical secondary standard
Livello qualitativo
agenzia
traceable to USP 1187091
Famiglia di API
dibutyl sebacate
CdA
current certificate can be downloaded
tecniche
HPLC: suitable
gas chromatography (GC): suitable
Indice di rifrazione
n20/D 1.441 (lit.)
P. eboll.
178-179 °C/3 mmHg (lit.)
Densità
0.936 g/mL at 25 °C (lit.)
applicazioni
pharmaceutical (small molecule)
Formato
neat
Temperatura di conservazione
2-30°C
Stringa SMILE
CCCCOC(=O)CCCCCCCCC(=O)OCCCC
InChI
1S/C18H34O4/c1-3-5-15-21-17(19)13-11-9-7-8-10-12-14-18(20)22-16-6-4-2/h3-16H2,1-2H3
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Descrizione generale
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dibutyl sebacate is a commonly used plasticizer, which can be synthesized by the reaction of butyl alcohol and sebacyl chloride or by the distillation of sebacic acid with butyl alcohol in the presence of concentrated hydrochloric acid in benzene solution.
Applicazioni
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Risultati analitici
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Altre note
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Nota a piè di pagina
To see an example of a Certificate of Analysis for this material enter LRAA9029 in the slot below. This is an example certificate only and may not be the lot that you receive.
Prodotti consigliati
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
366.8 °F - open cup
Punto d’infiammabilità (°C)
186 °C - open cup
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Burdock AG et al.
Encyclopedia of Food & Color Additives, 1 (1997)
D Serp et al.
Biotechnology and bioengineering, 82(1), 103-110 (2003-02-06)
The bioconversion of L-phenylalanine to 2-phenylethanol by Saccharomyces cerevisiae in fed-batch experiments has shown that concentrations of 2-phenylethanol of >2.9 g/L have a negative impact on the oxidative capacity of the yeast. Without tight control on ethanol production, and hence
Sogol Kangarlou et al.
International journal of pharmaceutics, 356(1-2), 153-166 (2008-03-22)
This research was conducted to investigate the physico-mechanical characteristics of the EC-based coating membranes plasticized with two informal ingredients of vitamin resources, cholecalciferol and alpha-tocopherol, with respect to the commercial plasticizer DBS. Proceeding the experiment, free thin polymer sheetings of
E Oh et al.
International journal of pharmaceutics, 188(2), 203-219 (1999-10-16)
The surface free energy parameters of ethylcellulose (EC) films were determined using the Lifshitz-van der Waals/acid-base approach and the influence of plasticizers on their surface energetics was assessed. Films were prepared by dip-coating glass slides in organic solvents containing EC
A Wyss et al.
Biotechnology and bioengineering, 91(2), 227-236 (2005-05-26)
The activity of penicillin acylase has been studied in aqueous and organic solvents, as free enzyme as well as immobilized within the membrane of liquid-core capsules. The activity of the enzyme is inhibited by the accumulation of the products of
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