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Documenti

K2012

Sigma-Aldrich

Ketoprofen

meets USP testing specifications

Sinonimo/i:

2-(3-Benzoylphenyl)propionic acid

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About This Item

Formula empirica (notazione di Hill):
C16H14O3
Numero CAS:
22071-15-4
Peso molecolare:
254.28
Numero CE:
244-759-8
Numero MDL:
MFCD00055790
Codice UNSPSC:
41116107
ID PubChem:
24896217
NACRES:
NA.21

agenzia

USP/NF
meets USP testing specifications

Livello qualitativo

200

Forma fisica

solid

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)
DKYWVDODHFEZIM-UHFFFAOYSA-N

Informazioni sul gene

human ... ALB(213) , IL8RA(3577) , PTGS1(5742) , PTGS2(5743)

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Applicazioni


  • A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery.: Although not exclusively focused on ketoprofen, this study details a novel adhesive for transdermal delivery, highlighting methods that could be adapted for enhancing the delivery of ketoprofen, thus being of interest to biochemists specializing in transdermal drug formulations (Fang et al., 2024).

Azioni biochim/fisiol

Non-steroidal anti-inflammatory compound that is selective for COX-1.

Pittogrammi

Skull and crossbonesEnvironment
GHS06,GHS09

Avvertenze

Danger

Indicazioni di pericolo

H301,H315,H319,H400

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
0000333417
0000333416
SLCR5202
SLCQ7896
SLCF3406

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Ibuprofen sodium salt ≥98% (GC)

Supelco

I1892

Ibuprofen sodium salt

Diclofenac

Sigma-Aldrich

D6899

Diclofenac

Metiliparaben Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1012

Metiliparaben

Ibuprofene ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofene

Ikram Ullah Khan et al.
International journal of pharmaceutics, 441(1-2), 809-817 (2012-12-26)
Microchannels based microfluidic systems are able to obtain monodispersed microparticles but are limited by cost, time and channel clogging. We succeeded in on the fly encapsulation of high ketoprofen contents in acrylate-based copolymer microbeads by environment friendly UV induced free
Elisabeth Christiansen et al.
Journal of medicinal chemistry, 54(19), 6691-6703 (2011-08-23)
The free fatty acid receptor 1 (FFA1, also known as GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and is recognized as an interesting new target for treatment of type 2 diabetes. Several series of selective FFA1 agonists are already
F Jamali et al.
Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the
Nathalie C Newby et al.
Journal of dairy science, 96(3), 1511-1520 (2013-01-22)
Surgical correction of left displaced abomasum (LDA) is common in lactating dairy cattle. Despite the growing acceptance that abdominal surgery is painful, few cows are administered analgesia following LDA surgery. The objective of this research was to examine the effect
Marcello Allegretti et al.
Journal of medicinal chemistry, 48(13), 4312-4331 (2005-06-25)
The CXC chemokine CXCL8/IL-8 plays a major role in the activation and recruitment of polymorphonuclear (PMN) cells at inflammatory sites. CXCL8 activates PMNs by binding the seven-transmembrane (7-TM) G-protein-coupled receptors CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2
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