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Documenti fondamentali

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D0513

Supelco

Dibucaine

analytical standard

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Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C20H29N3O2
Numero CAS:
85-79-0
Peso molecolare:
343.46
Numero CE:
201-632-1
Numero MDL:
MFCD00047595
Codice UNSPSC:
41116107
ID PubChem:
24893238

Grado

analytical standard

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

Formato

neat

Stringa SMILE

CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1

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Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Potent, long-acting local anesthetic

Pittogrammi

Environment
GHS09

Indicazioni di pericolo

H411

Consigli di prudenza

P273 - P391 - P501

Classi di pericolo

Aquatic Chronic 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
049K1165
067K1134
066K1236
129H1011
086H1018

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A Seelig
Cell biology international reports, 14(4), 369-380 (1990-04-01)
The interaction between lipids and water soluble amphiphiles was investigated by means of a monolayer technique, monitoring the area increase at constant surface pressure. The area increase could be quantitated and binding isotherms at different surface pressures were measured. A
M Laura Parnas et al.
American journal of clinical pathology, 135(2), 271-276 (2011-01-14)
Butyrylcholinesterase (BChE) metabolizes the paralytic succinylcholine. Extended paralysis occurs in people with inherited BChE variants that may be identified by measuring BChE activity with and without the inhibitor dibucaine to calculate a dibucaine number (DN). Accurate phenotyping requires phenotype-specific BChE
Jamie Nelsen et al.
Pediatric emergency care, 25(10), 670-673 (2009-10-17)
Dibucaine is considered one of the most potent and consequently toxic amide anesthetics available, and despite withdrawal from the US market as a spinal anesthetic, it remains accessible as an over-the-counter preparation in the United States. Dibucaine exposures in children
Thaïs Souto-Padrón et al.
Parasitology research, 99(4), 317-320 (2006-04-14)
Although local anesthetics (LA) are considered primarily Na+-channel blockers in the past decade, an alternative action of LA as inhibitors of fusion among compartments of the endocytic/exocytic pathways was described. In epimastigote forms of Trypanosoma cruzi, we observed that 50
Zhicheng Wang et al.
Archives of biochemistry and biophysics, 495(2), 136-143 (2010-01-12)
There are evidence that both a disintegrin and metalloproteinase 17 (ADAM17) and calpain are involved in platelet glycoprotein (GP)Ibalpha ectodomain cleavage. However, the relationship between the two enzymes in the shedding process remains unclear. Here we show that calcium ionophore
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