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91299

Supelco

Isobutyryl-L-carnitine

analytical standard

Sinonimo/i:

(2R)-3-Carboxy-N,N,N-trimethyl-2-(2-methyl-1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine isobutyryl ester, iC4-Carnitine

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About This Item

Formula empirica (notazione di Hill):
C11H21NO4
Numero CAS:
Peso molecolare:
231.29
Beilstein:
4138517
Numero MDL:
Codice UNSPSC:
41116107
NACRES:
NB.21

Grado

analytical standard

Livello qualitativo

Saggio

≥97.0% (HPLC)

Attività ottica

[α]/D -22.0±2.0°, c = 0.1 in H2O

Durata

limited shelf life, expiry date on the label

Impurezze

≤10.0% water (calculated from elemental analysis)

applicazioni

clinical testing

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

C[N+](C)(C)C[C@H](OC(C(C)C)=O)CC([O-])=O

InChI

1S/C11H21NO4/c1-8(2)11(15)16-9(6-10(13)14)7-12(3,4)5/h8-9H,6-7H2,1-5H3/t9-/m1/s1
LRCNOZRCYBNMEP-SECBINFHSA-N

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Descrizione generale

Isobutyryl-L-carnitine belongs to the acylcarnitines class of compounds. These compounds are produced from L-carnitine, which plays an important role in fatty acid metabolic pathways. The functions and roles of acyl-L-carnitines in various tissues like brain, heart, and muscle continue to attract much interest.

Applicazioni

Isobutyryl-L-carnitine may be used as an analytical reference standard for the separation and identification of underivatized isobutyryl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS). It may also be used as an analytical reference standard for the quantification of the analyte in human urine samples using liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS).

Prodotti consigliati

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Minzhi Peng et al.
Journal of chromatography. A, 1319, 97-106 (2013-10-31)
A simple HPLC-MS/MS method has been established to separate and identify underivatized acylcarnitine isomers. Human plasma samples were deproteinized and concentrated. Acylcarnitines were separated on a reverse phase column and detected with triple quadrupole linear ion trap mass spectrometry. Deuterium-labeled
Matrix effect?corrected liquid chromatography/tandem mass-spectrometric method for determining acylcarnitines in human urine
Abe K, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 468, 187-194 (2017)

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