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Sigma-Aldrich

4-Maleimidobutyric acid N-hydroxysuccinimide ester

≥98.0% (HPLC)

Sinonimo/i:

4-Maleimidobutyric acid N-succinimidyl ester, N-(γ-Maleimidobutyryloxy)succinimide, N-Succinimidyl 4-maleimidobutyrate, GMBS

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About This Item

Formula empirica (notazione di Hill):
C12H12N2O6
Numero CAS:
80307-12-6
Peso molecolare:
280.23
Beilstein:
6427689
Numero MDL:
MFCD00036817
Codice UNSPSC:
12352106
ID PubChem:
329759802
NACRES:
NA.25

Livello qualitativo

100

Saggio

≥98.0% (HPLC)

Impiego in reazioni chimiche

reagent type: linker

Punto di fusione

123-129 °C

Gruppo funzionale

NHS ester

Temperatura di conservazione

2-8°C

Stringa SMILE

O=C1N(CCCC(ON2C(CCC2=O)=O)=O)C(C=C1)=O

InChI

1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2
PVGATNRYUYNBHO-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 7-atom linker.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
BCCM0407
BCCM0539
BCBV0406
BCBV3389
SLBH6654

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We modified gold arrays with a glutathione (GSH) surface, and investigated high-throughput protein interactions with a spectral surface plasmon resonance (SPR) biosensor. We fabricated the GSH exterior on gold surfaces by successive modification with aminoethanethiol, 4-maleimidobutyric acid N-hydroxysuccinimide ester and
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