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50866

Supelco

[6]-Gingerol

analytical standard

Sinonimo/i:

3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-, 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone, 6-Gingerol

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About This Item

Formula empirica (notazione di Hill):
C17H26O4
Numero CAS:
Peso molecolare:
294.39
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥94.0% (HPLC)

Durata

expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1

InChI

1S/C17H26O4/c1-3-4-5-6-14(18)12-15(19)9-7-13-8-10-16(20)17(11-13)21-2/h8,10-11,14,18,20H,3-7,9,12H2,1-2H3/t14-/m0/s1
NLDDIKRKFXEWBK-AWEZNQCLSA-N

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Descrizione generale

[6]-Gingerol is a naturally occurring plant phenoland an active pungent constituent found in the rhizome of ginger, which is known to possess anti-inflammatory, anti-tumor and antioxidant properties and can hence, serve as a potential candidate in the treatment of cancer.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Bioactive compound found in ginger (Zingiber officinale) with antioxidant activity, which functions as an anti-inflammatory and antitumor agent. [6]-Gingerol down regulates proinflammatory cytokine release by macrophages. It has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

This compound is commonly found in plants of the genus: zingiber

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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Sigma-Aldrich

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[6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells
Lee SH, et al.
The Journal of Nutritional Biochemistry, 19, 313-319 (2008)
Induction of apoptosis in HL-60 cells by pungent vanilloids,[6]-gingerol and [6]-paradol
Lee Y and Surh J-Y
Cancer Letters, 134, 163-168 (1998)
[6]-Gingerol, a pungent ingredient of ginger, inhibits angiogenesis in vitro and in vivo
Kim C-E, et al.
Biochemical and Biophysical Research Communications, 335, 300-308 (2005)
Ganapathy Saravanan et al.
Journal of the science of food and agriculture, 94(14), 2972-2977 (2014-03-13)
Obesity represents a rapidly growing threat to the health of populations and diet intervention has been proposed as one of the strategies for weight loss. Ginger and its constituents have been used for their anti-flatulent, expectorant and appetising properties and
Zhenhao Li et al.
Journal of chromatography. A, 1376, 126-142 (2014-12-30)
In comparison with monotherapy in western medicine, traditional Chinese medicine (TCM) advocates combinational therapy for treating diseases and TCM formula is a representative for this approach. Despite of extensive clinical applications of TCM formulae, knowledge about their pharmacological activities, mechanisms

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