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Supelco

β-Alanine

analytical standard

Sinonimo/i:

β-Ala, 3-Aminopropionic acid

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About This Item

Formula condensata:
NH2CH2CH2COOH
Numero CAS:
Peso molecolare:
89.09
Beilstein:
906793
Numero CE:
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

Classi chimiche degli analiti

amino acids, peptides, proteins

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤0.3% water

Colore

white to off-white

Punto di fusione

202 °C (dec.) (lit.)

applicazioni

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Formato

neat

Stringa SMILE

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
UCMIRNVEIXFBKS-UHFFFAOYSA-N

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Descrizione generale

β-Alanine is a rate-limiting precursor of carnosine, a cytoplasmic dipeptide which is present in human skeletal muscles in high concentrations.

Applicazioni

β-Alanine may be used as a reference standard for the determination of β-alanine in:
  • Potato tubers by gas chromatography-mass spectrometry (GC-MS).
  • Human plasma, urine, and cerebrospinal fluid samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
  • Striatal microdialysis samples by high performance liquid chromatography-fluorescence detection (HPLC-FLD) with ortho-phthalaldehyde-mercaptoethanol derivatization.
  • Fermented soybean paste, Cheonggukjang, by GC-MS operating in selected-ion monitoring (SIM) mode and principal component analysis (PCA).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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Simultaneous analysis of metabolites in potato tuber by gas chromatography-mass spectrometry
Roessner U, et al.
The Plant Journal, 23(1), 131-142 (2000)
Metabolite profiling of Cheonggukjang, a fermented soybean paste, during fermentation by gas chromatography-mass spectrometry and principal component analysis
Park MK, et al.
Food Chemistry, 122(4), 1313-1319 (2010)
A rapid, sensitive method for quantitative analysis of underivatized amino acids by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Le A, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 944(1), 166-174 (2014)
Rapid and sensitive step gradient assays of glutamate, glycine, taurine and $\gamma$-aminobutyric acid by high-performance liquid chromatography-fluorescence detection with o-phthalaldehyde-mercaptoethanol derivatization with an emphasis on microdialysis samples
Piepponen TP and Skujins A
Journal of Chromatography. B, Biomedical Sciences and Applications, 757(2), 277-283 (2001)
?-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters
Derave W, et al.
Journal of Applied Physiology, 103(5), 1736-1743 (2007)

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