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292664

Sigma-Aldrich

N-tert-Butyl-α-(2-sulfophenyl)nitrone sodium salt

95%

Sinonimo/i:

2-SPBN sodium salt, 2-Sulfonatophenyl tert-butyl nitrone sodium salt

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About This Item

Formula condensata:
NaO3SC6H4CH=N(O)C(CH3)3
Numero CAS:
73475-11-3
Peso molecolare:
279.29
Numero MDL:
MFCD00012017
Codice UNSPSC:
12171500
ID PubChem:
24857605
NACRES:
NA.47

Saggio

95%

Forma fisica

powder or crystals

Punto di fusione

246 °C (dec.) (lit.)

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

[Na+].CC(C)(C)[N+](\[O-])=C\c1ccccc1S([O-])(=O)=O

InChI

1S/C11H15NO4S.Na/c1-11(2,3)12(13)8-9-6-4-5-7-10(9)17(14,15)16;/h4-8H,1-3H3,(H,14,15,16);/q;+1/p-1/b12-8-;
LAIQBHGUFDAJKL-JCTPKUEWSA-M

Applicazioni

Water-soluble, negatively-charged spin trap used to monitor aqueous phase of SDS micelles.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
10807DJ
21323LD
15211CZ
13513CQ
13427KR

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Catherine E Hobbs et al.
Pediatrics international : official journal of the Japan Pediatric Society, 50(4), 481-488 (2008-10-22)
The production of oxygen free radicals after perinatal hypoxia-ischemia is thought to play a critical role in the pathogenesis of the brain injury. Administration of anti-oxidants may thus be neuroprotective. The aim of the present study was to investigate the
Maria Molnar et al.
Upsala journal of medical sciences, 115(3), 163-168 (2010-07-20)
Hyperglycemia exacerbates focal ischemic brain damage supposedly through various mechanisms. One such mechanism is oxidative stress involving reactive oxygen and nitrogen species (RONS) production. Nitrones attenuate oxidative stress in various models of brain injury. Sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) can be
G J Wilde et al.
Journal of neurochemistry, 69(2), 883-886 (1997-08-01)
The relative roles of the superoxide and hydroxyl radicals in oxidative stress-induced neuronal damage were investigated using organotypic hippocampal slice cultures. Cultures exposed to 100 microM duroquinone, a superoxide-generating compound, for 3 h developed CA1-selective lesions over a period of
Steven L Peterson et al.
Neurotoxicology, 26(6), 969-979 (2005-05-14)
The status epilepticus (SE) induced in rats by lithium-pilocarpine (Li-pilo) shares many common features with soman-induced SE including extensive limbic neuropathology. Reactive oxygen species are hypothesized to play a role in the SE induced neuropathology and we propose that the
O A Andreassen et al.
Neuroreport, 12(15), 3371-3373 (2001-11-17)
There is substantial evidence implicating excitotoxicity and oxidative damage in the pathogenesis of Huntington's disease (HD). We therefore examined whether the antioxidants 2-sulpho-tert-phenyibutyinitrone (S-PBN) and alpha-lipoic acid could exert neuroprotective effects in transgenic mouse models of HD. S-PBN showed no
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