10602370001
Roche
Plasmin, bovine
from bovine plasma
Sinonimo/i:
Plasmin
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About This Item
Prodotti consigliati
Origine biologica
bovine plasma
Stato
suspension
Attività specifica
≥2 units/mg protein (At 25 °C with Chromozym PL as the substrate.)
PM
Mr ~85 kDa
Confezionamento
pkg of 1 mL (5 U)
Produttore/marchio commerciale
Roche
pH ottimale
8.9
Condizioni di spedizione
wet ice
Temperatura di conservazione
2-8°C
Descrizione generale
Plasmin is derived from the proteolytic cleavage of its precursor plasminogen. Human Plasmin is made up of two polypeptide chains. The polypeptide chains are connected via disulfide bridges.
Specificità
Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin.
Applicazioni
Plasmin from bovine has been used as a standard for assessing plasmin biosensors and for proteolytic assays.
Azioni biochim/fisiol
Plasmin plays an important role in proteolysis and fibrinolysis. It possesses inflammatory activity. Plasmin is also involved in the hydrolysis of peptide bonds following arginine or lysine. It also cleaves hormones like glucagon, thrombopoietin and growth hormones. Plasmin plays a role in cleavage of complement factors like C3 and C5, coagulation factors V and VIII, matrix proteins, growth factors, E-cadherins and metalloproteinase.
Stato fisico
Suspension in 3.2 M ammonium sulfate solution
Altre note
For life science research only. Not for use in diagnostic procedures.
Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
does not flash
Punto d’infiammabilità (°C)
does not flash
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