10171832001
Roche
Aldehyde Dehydrogenase
from yeast
Sinonimo/i:
Aldehyde dehydrogenase
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About This Item
Prodotti consigliati
Origine biologica
yeast
Livello qualitativo
Forma fisica
lyophilized
Attività specifica
~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.)
Confezionamento
pkg of 250 U
Produttore/marchio commerciale
Roche
pH ottimale
8.75
Malattie correlate
cancer
Temperatura di conservazione
2-8°C
Descrizione generale
Aldehyde dehydrogenase (ALDH) is a soluble enzyme and its activity depends on potassium ions and cysteine. The family of ALDH comprises of 19 genes in human. ALDH gene is expressed in the nucleus, cytosol, mitochondria and endoplasmic reticulum of the cell. ALDH is a component of nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH) recycling systems.
Applicazioni
Aldehyde Dehydrogenase has been used to evaluate fiber-optic biosensors for measurement of acetaldehyde (AcH) in liquid phase (AcH biosensor).
Azioni biochim/fisiol
Aldehyde dehydrogenase (ALDH) regulates the non-P450 aldehyde reduction enzyme system. It protects the cell from the effects of toxic aldehydes. Mutations in this gene are associated with Sjogren Larsson syndrome, Larsson syndrome, type II hyperprolinemia and cancer. ALDH takes part in the oxidation of aldehydes to acids. ALDH-2 lowers cardiac ischemia, which arises due to myocardial infarction or post cardiac surgery.
Qualità
Contaminants: <0.01% “NADH oxidase”, ADH, and LDH each
Stato fisico
Enzyme is stabilized with potassium phosphate buffer, pH approximately 6.
Altre note
For life science research only. Not for use in diagnostic procedures.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Inhalation - STOT RE 2
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
does not flash
Punto d’infiammabilità (°C)
does not flash
Certificati d'analisi (COA)
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