MAB3729

Anti-c-met Antibody, clone 4AT44

clone 4AT44, Chemicon^®, from mouse

• Sinonimo/i: Hepatocyte Growth Factor Receptor, HGFR
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 4AT44, monoclonal
• Reattività contro le specie: mouse, human
• Produttore/marchio commerciale: Chemicon^®
• tecniche: western blot: suitable
• Isotipo: IgG1
• N° accesso NCBI: NP_000236.2
• N° accesso UniProt: P08581
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... MET(4233) ; mouse ... Met(17295)

Descrizione

Specificità

Reacts with c-met/HGFR (Hepatocyte growth factor receptor). The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for c-met is hepatocyte growth factor/scatter factor (HGF/SF) and while normal HGF/SF-Met signaling is required for embryonic development, abnormal c-met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.

Immunogeno

Purified recombinant catalytic domain of human Met

Applicazioni

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

This Anti-c-met Antibody, clone 4AT44 is validated for use in WB for the detection of c-met.

Western Blot: 1:100-1:500.

ELISA (direct): 1:1,000

Optimal working dilutions must be determined by the end user.

Linkage

Replaces: 04-1051

Stato fisico

Format: Purified

Protein G purified immunoglobulin. Liquid in PBS containing 0.09% sodium azide.

Stoccaggio e stabilità

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable