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GR01

Anti-EGFR (Ab-1) Mouse mAb (528)

Name: Anti-EGFR (Ab-1) Mouse mAb (528)
Brand: MM

liquid, clone 528, Calbiochem^®

Sinonimo/i:

Anti-Epidermal Growth Factor Receptor

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Informazioni su questo articolo

NACRES:

NA.43

UNSPSC Code:

12352203

Clone:

528, monoclonal

Species reactivity:

human

Application:

—

Citations:

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biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

528, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

should not react with

mouse, rat

manufacturer/tradename

Calbiochem^®

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Questo articolo	MABF119	GR11	SAB4500714
Sigma-Aldrich GR01 Anti-EGFR (Ab-1) Mouse mAb (528)	Sigma-Aldrich MABF119 Anti-EGFR Antibody, clone 528 (Azide-free)	Sigma-Aldrich GR11 Anti-IGF-IR (Ab-1) Mouse mAb (αIR3)	Sigma-Aldrich SAB4500714 Anti-EGFR antibody produced in rabbit
species reactivity human	species reactivity human	species reactivity human	species reactivity human, rat, mouse
Gene Information human ... EGFR(1956) mouse ... Egfr(13649) rat ... Egf(25313)	Gene Information human ... EGFR(1956)	Gene Information human ... IGF1R(3480)	Gene Information human ... EGFR(1956)
antibody form purified antibody	antibody form purified antibody	antibody form purified antibody	antibody form affinity isolated antibody
clone 528, monoclonal	clone 528, monoclonal	clone αIR3, monoclonal	clone polyclonal
biological source mouse	biological source mouse	biological source mouse	biological source rabbit
form liquid	form -	form liquid	form buffered aqueous solution

General description

Anti-EGFR (Ab-1), mouse monoclonal, clone 528, recognizes EGF receptor protein in A431 cells and normal skin. It is validated for use in ELISA, IF, IP, IHC (frozen,paraffin) & neutralization studies.

Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with NS-1 mouse myeloma cells (see application references. Recognizes the ~170 kDa EGF receptor.

Recognizes the ~170 kDa EGF receptor protein in A431 cells and normal skin.

Application

Flow Cytometry (5 µg/ml)

Frozen Sections (2.5 µg/ml)

Immunofluorescence (5 µg/ml)

Immunoprecipitation(1 µg/sample)

Neutralization Studies (see comments and application references)

Paraffin Sections (see application references)

Packaging

Please refer to vial label for lot-specific concentration.

Analysis Note

Negative Control
HL-60 cells or human brain

Positive Control
A-431 or normal skin tissue

Other Notes

Hunter T. 1984. Nature311, 414.
Masui, H., et al. 1984. Cancer Res.44, 1002.
Reynolds, F. H., Jr., et al. 1981. Nature 292, 259.
Ushiro, H. and Cohen, S. 1980. J. Biol. Chem.255, 8363.

This antibody inhibits EGF binding to its receptor and is an antagonist of in vivo EGF-stimulated tyrosine kinase activity (see application references). Also inhibits A431 tumor formation in nude mice. For neutralization studies, use Cat. No. GR01L; Cat. No. GR01 contains azide, which is toxic to cells. Antibody should be titrated for optimal results in individual systems.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Classe di stoccaggio

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Numero articolo commerciale globale

SKU	GTIN
GR01-100UG	04055977220162

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