AB10439

Anti-PACSIN1 Antibody, NT

from rabbit

• Sinonimo/i: protein kinase C and casein kinase substrate in neurons 1, syndapin I
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: human, mouse
• tecniche: immunohistochemistry: suitable (paraffin); western blot: suitable
• N° accesso UniProt: Q9BY11
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... PACSIN1(29993)

Descrizione

Descrizione generale

PACSINs, also known as syndapins, are a protein family consisting of three members that have been implicated in synaptic vesicular membrane trafficking and regulation of dynamin-mediated endocytotic processes (Cuajungco, 2006). It is presumed that all isoforms bind Dynamin, Synaptojanin 1 and N-WASP through their Src homology 3 domains. While PACSIN1 appears to be restricted to neural tissues, two PACSINs are more widespread with PACSIN2 being ubiquitously expressed and PACSIN3 present mainly in skeletal muscle, heart and lung (Modregger, 2001). PACSIN1 has been implicated as playing a central role in synaptic vesicle recycling (Kessels, 2004). Expected molecular weight is 51 kDa.

Specificità

Reactivity with other species has not been tested.

The antibody recognizes human PACSIN1.

Immunogeno

KLH conjugated synthetic peptide selected from the N-terminal region of human PACSIN1.

Applicazioni

Anti-PACSIN1 Antibody, N-terminus detects level of PACSIN1 & has been published & validated for use in WB, IH(P).

Qualità

Evaluated on a representative lot by Western blot on mouse brain lysate using a 1:100 - 1:500 dilution of Anti-PACSIN1.

Descrizione del bersaglio

~57 kDa

Stato fisico

Format: Purified

PBS containing 0.09% NaN3.

Stoccaggio e stabilità

Maintain at 2-8ºC for up to 6 months from date of receipt. -20ºC is recommended for long term storage.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable