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1.52025

Supelco

Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns

L × I.D. 5 mm x 4.6 mm Guard Cartridges (3 pieces)

Sinonimo/i:

Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges (3 pieces)

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About This Item

Codice UNSPSC:
41115709
NACRES:
SB.52

product name

Chromolith® HighResolution RP-18 endcapped, L × I.D. 5 mm x 4.6 mm guard cartridges (3 pieces)

Materiali

PEEK column

Livello qualitativo

agenzia

suitable for ISO/CEN 6304.09
suitable for USP L1

Nome Commerciale

Chromolith®

Caratteristiche

endcapped
endcapped

Confezionamento

pkg of 3 ea

Grado di funzionalizzazione

15% Carbon loading
18% Carbon loading

Parametri

200 bar pressure
400 bar pressure
45 °C max. temp.
50 °C max. temp.

tecniche

HPLC: suitable
HPLC: suitable
LC/MS: suitable
mass spectrometry (MS): suitable (High)
mass spectrometry (MS): suitable (High)

Lungh. × diam. int. colonna

0.5 cm × 4.6 mm

Area superficiale

250 m2/g × 250 m2/g

Matrice

highly porous
monolithic silica
monolithic silica

Gruppo funzionale matrice

C18 bonding phase, octadecylsilane (ODS)
C18 bonding phase

Dimensione pori

1.15 μm macroporosity
1.5 μm macroporosity
15 nm mesoporosity
15 nm mesoporosity

operating pH range

2-7.5
2-7.5

Tecnica di separazione

reversed phase

Temperatura di conservazione

no temp limit

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Descrizione generale

Although the Chromolith® columns are well known for their robustness and longevity, guard columns are available to prolong the lifespan of Chromolith® analytical columns even further. These guard cartridges require a special holder.

Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges are extremely easy to use. The guard cartridges are simply added directly in front of the main column to protect it from chemical or mechanical contamination. Due to the benefits of monolithic technology, and the convenience of Chromolith® guard columns, they are also popular for use with classical particulate columns. Moreover, guard columns can be used as trap columns when large sample volumes are to be injected. Guard columns should be changed frequently in order to avoid excessive accumulation of impurities.

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges are used with the Chromolith® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Applicazioni


  • A Novel and Sensitive LC-MS/MS Method for the Quantitation of Ceftiofur in Pharmaceutical Preparations and Milk Samples.: This study, conducted by Levent S, Özcan S, Geven A, and Can NÖ, presents a new LC-MS/MS method utilizing Chromolith® HighResolution RP-18 endcapped columns. The method provides high sensitivity and specificity for the quantitation of ceftiofur, a veterinary antibiotic, in both pharmaceutical preparations and milk samples, demonstrating its potential for robust analytical applications in pharmaceutical and food safety contexts (Levent et al., 2021).

Note legali

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

11 - Combustible Solids


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Articoli

Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.

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