09-814
Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)
serum, from rabbit
Sinonimo/i:
dimethyl-arginine, asymmetric
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
rabbit
Livello qualitativo
Forma dell’anticorpo
serum
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Reattività contro le specie
mouse
Reattività contro le specie (prevista in base all’omologia)
rat (based on 100% sequence homology), human (based on 100% sequence homology)
tecniche
western blot: suitable
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
unmodified
Descrizione generale
Asymmetrical dimethlarginine (ADMA) is an endogenous, L-arginine metabolite arising from the proteolysis of methylated arginine containing proteins and is a known inhibitor of nitric oxide synthase (NOS). In various studies, ADMA has been observed as having a regulatory role in cell motility and the actin cytoskeleton. Elevated levels of ADMA are associated with sporadic FSGS, coronary artery disease, hypertension, peripheral arterial occlusive disease, obesity, stroke, preeclampsia, and cardiovascular mortality/morbidity in patients with diabetic nephropathy.
Specificità
This antibody recognizes dimethylated arginines.
Immunogeno
KLH-conjugated linear peptide containing asymmetric dimethyl-arginine-glycine repeats.
Applicazioni
Detect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.
Qualità
Evaluated by Western Blot in PRMT1 treated and untreated MEF cell lysates.
Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.
Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.
Descrizione del bersaglio
Multiple. This antibody detects proteins containing asymmetrical dimethylated arginines.
Risultati analitici
Control
PRMT1 treated and untreated MEF cell lysates
PRMT1 treated and untreated MEF cell lysates
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Certificati d'analisi (COA)
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