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810154P

Avanti

16:0-12:0 NBD PE

Avanti Research - A Croda Brand 810154P, powder

Sinonimo/i:

1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoethanolamine

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1 MG
283,00 €

About This Item

Formula empirica (notazione di Hill):
C39H68N5O11P
Numero CAS:
Peso molecolare:
813.96
Numero MDL:
Codice UNSPSC:
12352211
NACRES:
NA.25

283,00 €


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Saggio

>99% (TLC)

Stato

powder

Confezionamento

pkg of 1 × 1 mg (810154P-1mg)
pkg of 5 × 1 mg (810154P-5mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand 810154P

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Descrizione generale

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe localized at the membrane interface.[1][2] It possess fluorescent NBD label attached to the headgroup of phosphatidylethanolamine (PE).[2] PE is the parent compound for phosphatidylcholine and phosphatidylethanolamine synthesis[3] and is mostly enriched in brain.[4]

Applicazioni

16:0-12:0 NBD PE has been used in lipid extraction assay and in vitro phospholipid fluorescence resonance energy transfer (FRET) assays.[5] It is suitable for the determination of enzyme substrate specificity of lipoteichoic acid synthase (LtaS).[6][7][6]

Azioni biochim/fisiol

Phosphoethanolamine (PE) plays a vital role in the prevention of tumor proliferation.[3] N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) monitors the Red edge excitation shift (REES) phenomenon with the unique motional and dielectric properties it possesses.[1]

Confezionamento

5 mL Amber Glass Screw Cap Vial (810154P-1mg)
5 mL Amber Glass Screw Cap Vial (810154P-5mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids


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Theoretical Study of Phosphoethanolamine: A Synthetic Anticancer Agent with Broad Antitumor Activity
Lorenzo VP, et al.
Journal of Chemistry, 2016 (2016)
Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
Ouma Onguka et al.
The Journal of biological chemistry, 290(20), 12744-12752 (2015-04-02)
Phosphatidylethanolamine (PE) is a major cellular phospholipid that can be made by four separate pathways, one of which resides in the mitochondrion. The mitochondrial enzyme that generates PE is phosphatidylserine decarboxylase 1 (Psd1p). The pool of PE produced by Psd1p
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in
Maria Mercedes Palomino et al.
Microbiology (Reading, England), 159(Pt 11), 2416-2426 (2013-09-10)
The probiotic Gram-positive bacterium Lactobacillus casei BL23 is naturally confronted with salt-stress habitats. It has been previously reported that growth in high-salt medium, containing 0.8 M NaCl, leads to modifications in the cell envelope of this bacterium. In this study

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