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N17602

Sigma-Aldrich

5-Nitroindole

98%

Sinonimo/i:

NSC 520594

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About This Item

Formula empirica (notazione di Hill):
C8H6N2O2
Numero CAS:
6146-52-7
Peso molecolare:
162.15
Beilstein:
383777
Numero CE:
228-153-0
Numero MDL:
MFCD00005673
Codice UNSPSC:
12352100
ID PubChem:
24897523
NACRES:
NA.22

Saggio

98%

Forma fisica

powder

Punto di fusione

140-142 °C (lit.)

Stringa SMILE

[O-][N+](=O)c1ccc2[nH]ccc2c1

InChI

1S/C8H6N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-5,9H
OZFPSOBLQZPIAV-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

Reactant for preparation of:
  • Pharmaceutically active 2-oxo-1-pyrrolidine analogues
  • Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Protein Kinase Inhibitors and antiproliferative agents
  • Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)
  • Antifungal agents
  • Cannabinoid receptor type 1 (CB1) antagonists
  • Potential anticancer agents
  • Potential antivascular agents
  • Selective Anti-leukemic agents
  • Anti human immunodeficiency virus subtype 1 (HIV-1) agents

Pittogrammi

CorrosionExclamation mark
GHS05,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H318

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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5-Nitroisatin 97%

Sigma-Aldrich

N17807

5-Nitroisatin

2′-Deoxyinosine ≥98%

Sigma-Aldrich

D5287

2′-Deoxyinosine

2-Phenylindole technical grade, 95%

Sigma-Aldrich

P26600

2-Phenylindole

5-Iodoindole 97%

Sigma-Aldrich

563838

5-Iodoindole

Wengen Ouyang et al.
Journal of chemical theory and computation, 16(1), 666-676 (2019-12-10)
The importance of many-body dispersion effects in layered materials subjected to high external loads is evaluated. State-of-the-art many-body dispersion density functional theory calculations performed for graphite, hexagonal boron nitride, and their heterostructures were used to fit the parameters of a
Junbin Zhang et al.
Chembiochem : a European journal of chemical biology, 13(13), 1940-1945 (2012-08-14)
During the formation of RNA-induced silencing complex (RISC), the passenger and guide strand of an siRNA duplex separate from each other to generate an active RISC complex. Accumulating evidence shows that an siRNA passenger strand can also assemble into a
Caroline Crey-Desbiolles et al.
Nucleic acids research, 33(5), 1532-1543 (2005-03-16)
Universal DNA base analogs having photocleavable properties would be of great interest for development of new nucleic acid fragmentation tools. The photocleavable 7-nitroindole 2'-deoxyribonucleoside d(7-Ni) was previously shown to furnish a highly efficient approach to photochemically trigger DNA backbone cleavage
D Loakes et al.
Nucleic acids research, 23(13), 2361-2366 (1995-07-11)
3-Nitropyrrole and 5-nitroindole have been assessed as universal bases in primers for dideoxy DNA sequencing and in the polymerase chain reaction (PCR). In contrast to a previous report, we have found that the introduction of more than one 3-nitropyrrole residue
S Ball et al.
Nucleic acids research, 26(22), 5225-5227 (1998-11-04)
Studies have been carried out on the use of octamer oligonucleotides tailed with different base analogues as primers in cycle sequencing reactions. 5-Nitroindole tails improved the performance as primers of a number of octamers. A tail length of three or
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