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M29304

Sigma-Aldrich

N-Methylaniline

98%

Sinonimo/i:

Monomethylaniline

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25 G
32,50 €
500 G
63,60 €
1 KG
72,80 €

32,50 €


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Cambia visualizzazione
25 G
32,50 €
500 G
63,60 €
1 KG
72,80 €

About This Item

Formula condensata:
C6H5NHCH3
Numero CAS:
Peso molecolare:
107.15
Beilstein:
741982
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

32,50 €


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Saggio

98%

Stato

liquid

Indice di rifrazione

n20/D 1.571 (lit.)

P. ebollizione

196 °C (lit.)

Punto di fusione

−57 °C (lit.)

Densità

0.989 g/mL at 25 °C (lit.)

Stringa SMILE

CNc1ccccc1

InChI

1S/C7H9N/c1-8-7-5-3-2-4-6-7/h2-6,8H,1H3
AFBPFSWMIHJQDM-UHFFFAOYSA-N

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Applicazioni

N-Methylaniline is a general reagent used:
  • In the preparation of phosphoramidite ligands for the rhodium-catalyzed asymmetric hydroboration.[1]
  • As a formylating reagent in the C3-selective formylation of indoles.[2]
  • In the synthesis of a rhodol-based fluorescent probe, HKGreen-3, for sensing peroxynitrite.[3]
  • As a key starting material in the synthesis of AKT (protein kinase B) inhibitor-IV.[4]

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - STOT RE 2 Oral

Organi bersaglio

Liver,spleen,Bone marrow

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

185.0 °F - closed cup

Punto d’infiammabilità (°C)

85 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Certificati d'analisi (COA)

Lot/Batch Number

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I clienti hanno visto anche

Efficient amide-directed catalytic asymmetric hydroboration.
Smith S M, et al.
Journal of the American Chemical Society, 130(12), 3734-3735 (2008)
Synthesis and biological evaluation of analogues of AKT (protein kinase B) inhibitor-IV.
Sun Q, et al.
Journal of Medicinal Chemistry, 54(5), 1126-1139 (2011)
HKGreen-3: a rhodol-based fluorescent probe for peroxynitrite.
Peng T and Yang D
Organic Letters, 12(21), 4932-4935 (2010)
Israel González et al.
Organic letters, 11(8), 1677-1680 (2009-04-10)
N-Methylanilines are readily synthesized in high yields through the copper(II)-promoted coupling of anilines and methylboronic acid. This method represents a new approach for the selective monomethylation of anilines, and it is the first reported example of a Chan-Lam coupling involving
Jonathan L Sessler et al.
Chemical communications (Cambridge, England), (14)(14), 1892-1894 (2005-03-30)
A novel porphyrin-fullerene dyad assembled through Watson-Crick hydrogen bonds is described; this system undergoes photoinduced electron transfer upon irradiation with visible light to produce a charge separated state that is substantially longer lived than that of previous dyads of this

Domande

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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