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Documenti

F6206

Sigma-Aldrich

4-Fluorobenzenesulfonyl chloride

98%

Sinonimo/i:

4-Fluorobenzene-1-sulfonyl chloride, p-Fluorobenzenesulfonyl chloride

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About This Item

Formula condensata:
FC6H4SO2Cl
Numero CAS:
349-88-2
Peso molecolare:
194.61
Beilstein:
2091633
Numero CE:
206-493-0
Numero MDL:
MFCD00007438
Codice UNSPSC:
12352100
ID PubChem:
24894904
NACRES:
NA.22

Saggio

98%

P. eboll.

95-96 °C/2 mmHg (lit.)

Punto di fusione

29-31 °C (lit.)

Stringa SMILE

Fc1ccc(cc1)S(Cl)(=O)=O

InChI

1S/C6H4ClFO2S/c7-11(9,10)6-3-1-5(8)2-4-6/h1-4H
BFXHJFKKRGVUMU-UHFFFAOYSA-N

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Categorie correlate

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H314

Classi di pericolo

Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

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Y A Chang et al.
Bioconjugate chemistry, 3(2), 200-202 (1992-03-01)
4-Fluorobenzenesulfonyl chloride (fosyl chloride), due to the strong electron-withdrawing property of its fluoride atom, is found to be an excellent activating agent for the covalent attachment of biologicals to a variety of solid supports (e.g. functionalized polystyrene microspheres, Sepharose beads
T H Liao et al.
Analytical biochemistry, 148(2), 365-375 (1985-08-01)
The reagent p-fluorobenzenesulfonyl chloride modifies the protein side chains of tyrosine, lysine, and histidine and the alpha-NH2 group. The p-fluorobenzenesulfonyl (Fbs-) group, identified by the 19F nuclear magnetic resonance signal, exhibits a different 19F chemical shift for each functional group
Umaprasana Ojha et al.
Langmuir : the ACS journal of surfaces and colloids, 25(11), 6319-6327 (2009-04-02)
Peptide surface modification of poly[(methyl methacrylate-co-hydroxyethyl methacrylate)-b-isobutylene-b-(methyl methacrylate-co-hydroxyethyl methacrylate)] P(MMA-co-HEMA)-b-PIB-b-P(MMA-co-HEMA) triblock copolymers with different HEMA/MMA ratios has been accomplished using an efficient synthetic procedure. The triblock copolymers were reacted with 4-fluorobenzenesulfonyl chloride (fosyl chloride) in pyridine to obtain the activated
Ning Li et al.
European journal of medicinal chemistry, 155, 531-544 (2018-06-18)
Ten novel symmetric 3,5-bis(arylidene)-4-piperidone derivatives (BAPs, 1-10) and fourteen dissymmetric BAPs (11-24) were synthesized and evaluated the cytotoxicity. All of the compounds have been screened for their anti-inflammatory activity characterized by evaluating their inhibitory effects on LPS-induced IL-6, TNF-α secretion.
Abdelaziz Houmam et al.
Physical chemistry chemical physics : PCCP, 14(1), 113-124 (2011-09-15)
Important aspects of the electrochemical reduction of a series of substituted arene sulfonyl chlorides are investigated. An interesting autocatalytic mechanism is encountered where the starting material is reduced both at the electrode and through homogeneous electron transfer from the resulting

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