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Sigma-Aldrich

4-Bromo-1-butyne

97%

Sinonimo/i:

1-Bromo-3-butyne

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5 G
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5 G
83,50 €

About This Item

Formula empirica (notazione di Hill):
C4H5Br
Numero CAS:
Peso molecolare:
132.99
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

83,50 €


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Livello qualitativo

Saggio

97%

Indice di rifrazione

n20/D 1.481

Densità

1.417 g/mL at 25 °C

Gruppo funzionale

alkyl halide
bromo

Stringa SMILE

BrCCC#C

InChI

1S/C4H5Br/c1-2-3-4-5/h1H,3-4H2
XLYOGWXIKVUXCL-UHFFFAOYSA-N

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Descrizione generale

4-Bromo-1-butyne is commonly used as a reactant. It serves as a source of alkyl halides for the introduction of bromo functionality into the molecule.[1]

Applicazioni

4-Bromo-1-butyne is used as a reactant in the synthesis of:
  • Macrocycles by cobalt-mediated [2+2+2] co-cyclotrimerization.[2]
  • 2,4,5-trisubstituted oxazoles by a gold-catalyzed formal [3+2] cycloaddition.[3]
  • Intramolecular 1,3-dipolar cycloaddition to synthesize 1,3,4-oxadiazoles.[4]
  • Lactones bearing alkynes for reductive cyclization in the preparation of azulene derivatives.[5]
  • Substituted α-pyrones by gold-catalyzed coupling reactions.[6]

Pittogrammi

FlameSkull and crossbones

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Oral - Flam. Liq. 3 - Skin Sens. 1

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

75.0 °F

Punto d’infiammabilità (°C)

23.9 °C

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Certificati d'analisi (COA)

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I clienti hanno visto anche

Intermolecular and Selective Synthesis of 2, 4, 5-Trisubstituted Oxazoles by a Gold-Catalyzed Formal [3+ 2] Cycloaddition.
Davies PW, et al.
Angewandte Chemie (International Edition in English), 50(38), 8931-8935 (2011)
Reductive Cyclization Cascades of Lactones Using SmI2- H2O.
Parmar D, et al.
Journal of the American Chemical Society, 133(8), 2418-2420 (2011)
Intramolecular Diels- Alder/1, 3-dipolar cycloaddition cascade of 1, 3, 4-oxadiazoles.
Elliott GI, et al.
Journal of the American Chemical Society, 128(32), 10589-10595 (2006)
A facile synthesis of N-C linked 1, 2, 3-triazole-oligomers
V Fiandanese, et al.
Tetrahedron, 67, 5254-5260 (2011)
Synthesis of macrocycles via cobalt-mediated [2+ 2+ 2] cycloadditions.
Bonaga LVR, et al.
Journal of the American Chemical Society, 127(10), 3473-3485 (2005)

Domande

1–2 di 2 domande  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

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