638013

4-Diphenylphosphanylbenzoic acid, 2-(trimethylsilyl)ethyl ester solution

0.5 M in THF

• Formula empirica (notazione di Hill): C₂₄H₂₇O₂PSi
• Numero CAS: 566190-45-2
• Peso molecolare: 406.53
• Numero MDL: MFCD07369722
• Codice UNSPSC: 12352108
• ID PubChem: 24882904

Proprietà

• Impiego in reazioni chimiche: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• Concentrazione: 0.5 M in THF
• Densità: 0.925 g/mL at 25 °C
• Gruppo funzionale: phosphine
• Stringa SMILE: C[Si](C)(C)CCOC(=O)c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C24H27O2PSi/c1-28(2,3)19-18-26-24(25)20-14-16-23(17-15-20)27(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17H,18-19H2,1-3H3; QTYUNPJLGFKKRV-UHFFFAOYSA-N

Descrizione

Applicazioni

4-Diphenylphosphanyl-benzoic acid 2-trimethylsilanyl-ethyl ester (DPPBE) was developed as an efficient alternative to triphenylphosphine in the Mitsunobu reaction since the phosphine oxide formed during the reaction can be easily removed during workup.

Reagent for:

• Synthesis of alkenes
• Methylation of aldehydes
• Mitsunobu reactions

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H319,H335,H351
• Consigli di prudenza: P210 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Classi di pericolo: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Rischi supp: EUH019
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): -4.0 °F - closed cup
• Punto d’infiammabilità (°C): -20 °C - closed cup